The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
CircRNA: functions and properties of a novel potential biomarker for cancer
S Meng, H Zhou, Z Feng, Z Xu, Y Tang, P Li, M Wu - Molecular cancer, 2017 - Springer
Circular RNAs, a novel class of endogenous noncoding RNAs, are characterized by their
covalently closed loop structures without a 5′ cap or a 3′ Poly A tail. Although the …
covalently closed loop structures without a 5′ cap or a 3′ Poly A tail. Although the …
Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke
B Han, Y Zhang, Y Zhang, Y Bai, X Chen, R Huang… - Autophagy, 2018 - Taylor & Francis
Circular RNAs (circRNAs) are highly expressed in the central nervous system and are
involved in the regulation of physiological and pathophysiological processes. However, the …
involved in the regulation of physiological and pathophysiological processes. However, the …
Circular RNA DLGAP4 ameliorates ischemic stroke outcomes by targeting miR-143 to regulate endothelial-mesenchymal transition associated with blood–brain …
Y Bai, Y Zhang, B Han, L Yang, X Chen… - Journal of …, 2018 - Soc Neuroscience
Circular RNAs (circRNAs) are highly expressed in the CNS and regulate physiological and
pathophysiological processes. However, the potential role of circRNAs in stroke remains …
pathophysiological processes. However, the potential role of circRNAs in stroke remains …
circRNA-miRNA-mRNA regulatory network in human lung cancer: an update
ZZ Liang, C Guo, MM Zou, P Meng, TT Zhang - Cancer cell international, 2020 - Springer
Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been
studied, probed and applied into several diseases, such as cardiovascular diseases …
studied, probed and applied into several diseases, such as cardiovascular diseases …
The potential of using blood circular RNA as liquid biopsy biomarker for human diseases
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …
[HTML][HTML] Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atherosclerosis in rabbits
F Zhang, R Zhang, X Zhang, Y Wu, X Li… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Atherosclerosis is a chronic and multifactorial inflammatory disease and is closely
associated with cardiovascular and cerebrovascular diseases. circRNAs can act as …
associated with cardiovascular and cerebrovascular diseases. circRNAs can act as …
Predicting CircRNA-disease associations via feature convolution learning with heterogeneous graph attention network
L Peng, C Yang, Y Chen, W Liu - IEEE Journal of Biomedical …, 2023 - ieeexplore.ieee.org
Exploring the relationship between circular RNA (circRNA) and disease is beneficial for
revealing the mechanisms of disease pathogenesis. However, a blind search for all possible …
revealing the mechanisms of disease pathogenesis. However, a blind search for all possible …
A novel circular RNA, circFAT1 (e2), inhibits gastric cancer progression by targeting miR-548g in the cytoplasm and interacting with YBX1 in the nucleus
J Fang, H Hong, X Xue, X Zhu, L Jiang, M Qin, H Liang… - Cancer letters, 2019 - Elsevier
In the present study, two circular RNA (circRNA) expression profiles in paired gastric cancer
(GC) tissues from the GEO database were examined. We identified a novel circRNA …
(GC) tissues from the GEO database were examined. We identified a novel circRNA …
Insights into the role of CircRNAs: biogenesis, characterization, functional, and clinical impact in human malignancies
Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …