Preeclampsia is a severe pregnancy complication globally, characterized by poor
placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs) exhibit …

Implantation of the embryo into the endometrium is a critical step in the establishment of
pregnancy and the failure of embryos to implant is a major limiting factor in the success of …

BACKGROUND Invasion by extravillous trophoblast into uterine decidua and myometrium
with remodeling of spiral arteries is essential for normal human pregnancy and is tightly …

BACKGROUND Recurrent pregnancy loss (RPL), defined as two or more miscarriages,
affects 3–5% of couples trying to establish a family. Despite extensive evaluation, no factor is …

Purpose Epidemiologic data suggest that in vitro fertilization (IVF) is associated with an
increased risk of disorders of placentation including preeclampsia and fetal growth …

Background Trophoblast cell (CTB) invasion into the maternal endometrium plays a crucial
role during human embryo implantation and placentation. This invasion is facilitated by the …

We aimed to determine the effect of YY1 expression on the expression profile of long
noncoding RNAs (lncRNAs) in trophoblasts, and we studied the involvement of certain …

For a successful pregnancy to occur, a predecidualized receptive endometrium must be
invaded by placental differentiated cells (extravillous trophoblast cells (EVTs)) and, at the …

BACKGROUND Crosstalk between human trophectoderm (TE) and endometrial cells during
the implantation window is a complex and not well-understood process. The aims of this …

Extravillous trophoblasts (EVTs) invade human decidua via sequential integrin-mediated
binding and proteolysis of basement membrane proteins in the extracellular matrix (ECM). In …