Aim To assess the effect of Cytochrome P450 2C9 (CYP 2C9) gene polymorphism on
pediatric warfarin maintenance dosage requirement. Methods A previously developed …

Studies on the effect of cytochrome P450 2C9 (CYP2C9), vitamin K epoxide reductase
complex subunit 1 (VKORC1), and cytochrome P450 4F2 (CYP4F2) polymorphisms on …

Purpose This study was conducted to determine the effect of UGT1A9 98T> C, CYP2B6
516G> T and CYP2C9 430C> T genetic polymorphisms on the pharmacokinetics of propofol …

What is known and objective Despite an apparently sound pharmacological basis, clinical
studies of genotype‐guided warfarin dosing have yielded mixed and conflicting results …

Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics
(PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a …

Long-term oral warfarin is recommended in pediatric Kawasaki disease patients with large
coronary artery aneurysms; however, heterogeneity is considerable. This study aimed to …

Warfarin is prescribed in patients with ventricular assist devices (VADs). Dosage depends
on several factors including the underlying genotype. These include polymorphisms of …

Abstract CYP2C9 and VKORC1-1639 G> A genes as the genetic factors significantly
influence the warfarin dose requirement in individuals. The patients with genetic variations …

Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics
(PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a …

Ovа studijа se bavi ispitivanjem potencijаlno zaštitinih efekata аgmаtina (AGM) nа razvoj
oksidаtivnog/nitrozativnog stresa u selektivno osetljivim strukturama mozga pacova nakon …