Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …

The exact patho-aetiology of systemic lupus erythematosus (SLE) remains elusive. An
extremely complicated and multifactorial interaction among various genetic and …

Objective To investigate the release of interferon‐α (IFNα)–inducing material by necrotic or
apoptotic cells, its properties, and the necessity of autoantibodies from systemic lupus …

Systemic lupus erythematosus (SLE) is a fairly heterogeneous autoimmune disease.
Impaired clearance functions for dying cells may explain accumulation of nuclear …

Deficiency of classical pathway complement components displays a hierarchical association
with the development of systemic lupus erythematosus (SLE). Individuals with deficiency of …

Inefficient and abnormal clearance of apoptotic cells (efferocytosis) contributes to systemic
autoimmune disease in humans and mice, and inefficient chromosomal DNA degradation by …

Immature dendritic cells (iDCs) do not mature after uptake of apoptotic cells and may play a
role in the induction of peripheral tolerance to self antigens derived from apoptotic material …

Systemic lupus erythematosus (SLE) is an autoimmune disease with very prominent chronic
inflammatory aspects that render into multiple symptoms and clinical signs. The precise …

Systemic lupus erythematosus (SLE) is a fairly heterogeneous autoimmune disease of
unknown etiology that mainly affects women in the childbearing age. SLE is a prototype type …

OBJECTIVES: To review current developments, regarding the pathophysiologic role of
monocytes and macrophages in systemic lupus erythematosus (SLE). METHODS: We …