[HTML][HTML] Cellular decision making and biological noise: from microbes to mammals
Cellular decision making is the process whereby cells assume different, functionally
important and heritable fates without an associated genetic or environmental difference …
important and heritable fates without an associated genetic or environmental difference …
Phenotypic plasticity's impacts on diversification and speciation
Phenotypic plasticity (the ability of a single genotype to produce multiple phenotypes in
response to variation in the environment) is commonplace. Yet its evolutionary significance …
response to variation in the environment) is commonplace. Yet its evolutionary significance …
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
A Petronis - Nature, 2010 - nature.com
Epigenetic modifications of DNA and histones might be crucial for understanding the
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …
Inherited epigenetic variation—revisiting soft inheritance
EJ Richards - Nature Reviews Genetics, 2006 - nature.com
Phenotypic variation is traditionally parsed into components that are directed by genetic and
environmental variation. The line between these two components is blurred by inherited …
environmental variation. The line between these two components is blurred by inherited …
Assessing the impact of transgenerational epigenetic variation on complex traits
F Johannes, E Porcher, FK Teixeira… - PLoS …, 2009 - journals.plos.org
Loss or gain of DNA methylation can affect gene expression and is sometimes transmitted
across generations. Such epigenetic alterations are thus a possible source of heritable …
across generations. Such epigenetic alterations are thus a possible source of heritable …
Transgenerational defense induction and epigenetic inheritance in plants
Rapidly accumulating evidence shows that herbivore and pathogen attack of plants can
generate particular defense phenotypes across generations. What was once thought to be …
generate particular defense phenotypes across generations. What was once thought to be …
Nongenetic inheritance and its evolutionary implications
R Bonduriansky, T Day - Annual Review of Ecology, Evolution …, 2009 - annualreviews.org
Modern evolutionary biology is founded on the Mendelian-genetic model of inheritance, but
it is now clear that this model is incomplete. Empirical evidence shows that environment …
it is now clear that this model is incomplete. Empirical evidence shows that environment …
The implications of nongenetic inheritance for evolution in changing environments
Nongenetic inheritance is a potentially important but poorly understood factor in population
responses to rapid environmental change. Accumulating evidence indicates that nongenetic …
responses to rapid environmental change. Accumulating evidence indicates that nongenetic …
Waddington's canalization revisited: developmental stability and evolution
Most species maintain abundant genetic variation and experience a range of environmental
conditions, yet phenotypic variation is low. That is, development is robust to changes in …
conditions, yet phenotypic variation is low. That is, development is robust to changes in …
Environmentally induced phenotypes and DNA methylation: how to deal with unpredictable conditions until the next generation and after
B Angers, E Castonguay, R Massicotte - Molecular Ecology, 2010 - Wiley Online Library
Organisms often respond to environmental changes by producing alternative phenotypes.
Epigenetic processes such as DNA methylation may contribute to environmentally induced …
Epigenetic processes such as DNA methylation may contribute to environmentally induced …