Abstract Characterization of the progression of cellular states during human embryogenesis
can provide insights into the origin of pediatric diseases. We examined the transcriptional …

Enzymatic methylation catalyzed by methyltransferases has a significant impact on many
human biochemical reactions. As the second most ubiquitous cofactor in humans, S …

The mammalian adrenal gland is composed of two distinct tissue types in a bidirectional
connection, the catecholamine-producing medulla derived from the neural crest and the …

The use of sacred values by humans to enforce cooperation has been seen throughout
human history, as demonstrated by philosophers like Marx and Aristotle observing that …

Glucocorticoids (GCs) are steroid hormones fundamental to the body's normal physiological
functions and are pivotal in fetal growth and development. During gestation, the mother's …

The field of cardiovascular fetal programming has emphasized the importance of the uterine
environment on postnatal cardiovascular health. Studies have linked increased fetal …

Background: Administration of antenatal glucocorticoids remains common practice for
treating preterm delivery. Antenatal glucocorticoid exposure increased the risk of developing …

In utero exposure to glucocorticoids in late gestation programs changes in cardiovascular
function. The objective of this study was to determine the degree to which angiotensin II …

Introduction: Rheumatoid arthritis (RA) can spontaneously improve during pregnancy.
However, a considerable proportion of patients can experience a flare and high disease …

Biochemical changes in utero may alter normal fetal development, resulting in disease later
in life, a phenomenon known as fetal programming. Recent epidemiological studies link fetal …