Phosphoinositides as membrane organizers
Phosphoinositides are signalling lipids derived from phosphatidylinositol, a ubiquitous
phospholipid in the cytoplasmic leaflet of eukaryotic membranes. Initially discovered for their …
phospholipid in the cytoplasmic leaflet of eukaryotic membranes. Initially discovered for their …
[HTML][HTML] Small extracellular vesicles: non-negligible vesicles in tumor progression, diagnosis, and therapy
X Zhou, Y Jia, C Mao, S Liu - Cancer Letters, 2023 - Elsevier
Small extracellular vesicles (sEVs) such as exosomes are nanoscale membranous particles
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
A phosphoinositide signalling pathway mediates rapid lysosomal repair
Lysosomal dysfunction has been increasingly linked to disease and normal ageing,.
Lysosomal membrane permeabilization (LMP), a hallmark of lysosome-related diseases …
Lysosomal membrane permeabilization (LMP), a hallmark of lysosome-related diseases …
Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites
Abnormal distribution of cellular cholesterol is associated with numerous diseases, including
cardiovascular and neurodegenerative diseases. Regulated transport of cholesterol is …
cardiovascular and neurodegenerative diseases. Regulated transport of cholesterol is …
Endoplasmic reticulum membrane contact sites, lipid transport, and neurodegeneration
A Guillén-Samander… - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
The Endoplasmic Reticulum (ER) is an endomembrane system that plays a multiplicity of
roles in cell physiology and populates even the most distal cell compartments, including …
roles in cell physiology and populates even the most distal cell compartments, including …
Phosphatidylserine transport in cell life and death
Phosphatidylserine (PS) is a negatively charged glycerophospholipid found mainly in the
plasma membrane (PM) and in the late secretory/endocytic compartments, where it …
plasma membrane (PM) and in the late secretory/endocytic compartments, where it …
Coordination of inter-organelle communication and lipid fluxes by OSBP-related proteins
A Arora, JH Taskinen, VM Olkkonen - Progress in lipid research, 2022 - Elsevier
Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) constitute one of the
largest families of lipid-binding/transfer proteins (LTPs) in eukaryotes. The current view is …
largest families of lipid-binding/transfer proteins (LTPs) in eukaryotes. The current view is …
Stay in touch with the endoplasmic reticulum
S Sun, G Zhao, M Jia, Q Jiang, S Li, H Wang… - Science China Life …, 2024 - Springer
The endoplasmic reticulum (ER), which is composed of a continuous network of tubules and
sheets, forms the most widely distributed membrane system in eukaryotic cells. As a result, it …
sheets, forms the most widely distributed membrane system in eukaryotic cells. As a result, it …
Low-density lipoprotein internalization, degradation and receptor recycling along membrane contact sites
MM Islam, I Hlushchenko, SG Pfisterer - Frontiers in Cell and …, 2022 - frontiersin.org
Low-density lipoprotein (LDL) internalization, degradation, and receptor recycling is a
fundamental process underlying hypercholesterolemia, a high blood cholesterol …
fundamental process underlying hypercholesterolemia, a high blood cholesterol …