[HTML][HTML] Quercetin attenuates neurotoxicity induced by iron oxide nanoparticles

A Bardestani, S Ebrahimpour, A Esmaeili… - Journal of …, 2021 - Springer
Iron oxide nanoparticles (IONPs) have been proposed as targeted carriers to deliver
therapeutic molecules in the central nervous system (CNS). However, IONPs may damage …

[HTML][HTML] Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action

P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …

Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: role of Nrf2/HO-1/Keap-1 signaling …

DA AbdElrazek, MA Ibrahim, NH Hassan, EI Hassanen… - Neurotoxicology, 2023 - Elsevier
Quercetin (Qu) is a powerful flavanol antioxidant that is naturally found in plants and is part
of the flavonoid family. Qu has a wide range of biological properties, such as …

[HTML][HTML] A comparative analysis of neuroprotective properties of taxifolin and its water-soluble form in ischemia of cerebral cortical cells of the mouse

EG Varlamova, NI Uspalenko, NV Khmil… - International Journal of …, 2023 - mdpi.com
Cerebral ischemia, and, as a result, insult, attacks up to 15 million people yearly in the world.
In this connection, the development of effective preventive programs and methods of therapy …

[HTML][HTML] Rutin attenuates D-galactose-induced oxidative stress in rats' brain and liver: molecular docking and experimental approaches

SM Saafan, SA Mohamed, AE Noreldin… - Food & Function, 2023 - pubs.rsc.org
Oxidative stress results from the imbalance between reactive oxygen species (ROS)
production and antioxidant defence and is primarily involved in aging. The current study …

Recent advances in the effects of dietary polyphenols on inflammation in vivo: Potential molecular mechanisms, receptor targets, safety issues, and uses of …

D Wang, T Wang, Z Zhang, Z Li, Y Guo, G Zhao… - Current Opinion in Food …, 2022 - Elsevier
High dietary intake of dietary polyphenols is associated with a decreased risk of chronic
diseases, especially in inflammation. However, mechanisms responsible for their anti …

[HTML][HTML] Cytoprotective properties of a new nanocomplex of selenium with taxifolin in the cells of the cerebral cortex exposed to ischemia/reoxygenation

EG Varlamova, VV Khabatova, SV Gudkov… - Pharmaceutics, 2022 - mdpi.com
The neuroprotective effect of the natural antioxidant taxifolin (TAX) is well known for
ischemic pathologies. However, the limitations of taxifolin application are described—poor …

Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics

AH El‐Far, SK Al Jaouni, X Li, J Fu - Phytotherapy Research, 2022 - Wiley Online Library
Glycolysis is the primary source of energy for cancer growth and metastasis. The shift in
metabolism from mitochondrial oxidative phosphorylation to aerobic glycolysis is called the …

Quercetin counteracts monosodium glutamate to mitigate immunosuppression in the thymus and spleen via redox-guided cellular signaling

D Das, A Banerjee, K Manna, D Sarkar, A Shil… - Phytomedicine, 2024 - Elsevier
Background Chronic inflammation brought on by oxidative stress can result in several
immunopathologies. Natural compounds with antioxidant characteristics, like quercetin …

[HTML][HTML] Ferroptosis preceded the onset of oxidative stress under acute ammonia exposure and quercetin relieved ammonia-induced ferroptosis of yellow catfish …

X Long, K He, M Zhang, H Jiang, X Dong, C Wang… - Aquaculture …, 2023 - Elsevier
Ammonia is the most common pollutant and stressor in the aquaculture environment and
can cause massive fish mortality. Its toxicity in fish is mainly related to the generation of …