From microbiome composition to functional engineering, one step at a time

SD Burz, S Causevic, A Dal Co… - Microbiology and …, 2023 - Am Soc Microbiol
Communities of microorganisms (microbiota) are present in all habitats on Earth and are
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …

[HTML][HTML] Evolutionary and ecological role of extracellular contractile injection systems: from threat to weapon

CM Heiman, J Vacheron, C Keel - Frontiers in Microbiology, 2023 - frontiersin.org
Contractile injection systems (CISs) are phage tail-related structures that are encoded in
many bacterial genomes. These devices encompass the cell-based type VI secretion …

Interspecies killing activity of Pseudomonas syringae tailocins

SL Weaver, L Zhu, S Ravishankar, M Clark… - …, 2022 - microbiologyresearch.org
Tailocins are ribosomally synthesized bacteriocins, encoded by bacterial genomes, but
originally derived from bacteriophage tails. As with both bacteriocins and phage, tailocins …

Pantailocins: phage-derived bacteriocins from Pantoea ananatis and Pantoea stewartii subsp. indologenes

SP Stice, HH Jan, HC Chen, L Nwosu… - Applied and …, 2023 - Am Soc Microbiol
Phage-derived bacteriocins are highly specific and effective antimicrobial molecules, which
have successfully been used as prophylactic treatments to prevent phytopathogen …

[HTML][HTML] Strategies for developing phages into novel antimicrobial tailocins

C Woudstra, AN Sørensen, MCH Sørensen… - Trends in …, 2024 - cell.com
Tailocins are high-molecular-weight bacteriocins produced by bacteria to kill related
environmental competitors by binding and puncturing their target. Tailocins are promising …

A phage tail–like bacteriocin suppresses competitors in metapopulations of pathogenic bacteria

T Backman, SM Latorre, E Symeonidi, A Muszyński… - Science, 2024 - science.org
Bacteria can repurpose their own bacteriophage viruses (phage) to kill competing bacteria.
Phage-derived elements are frequently strain specific in their killing activity, although there …

Genomic correlates of tailocin sensitivity in Pseudomonas syringae

DA Baltrus, S Weaver, L Krings, AE Nguyen - BioRxiv, 2023 - biorxiv.org
Phage derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial
genomes and deployed into the extracellular environment to target and kill sensitive cells …

A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria

T Backman, SM Latorre, E Symeonidi, A Muszyński… - bioRxiv, 2023 - biorxiv.org
Bacteriophages, the viruses of bacteria, are proposed to drive bacterial population
dynamics, yet direct evidence of their impact on natural populations is limited. Here we …

Marinomonas mediterranea synthesizes an R-type bacteriocin

P Lucas-Elío, T ElAlami, A Martínez… - Applied and …, 2024 - Am Soc Microbiol
Prophages integrated into bacterial genomes can become cryptic or defective prophages,
which may evolve to provide various traits to bacterial cells. Previous research on …

Historical advancements in understanding bacteriocins produced by rhizobacteria for their application in agriculture

S Fischer, V López-Ramírez, J Asconapé - Rhizosphere, 2024 - Elsevier
In the environment, microbes compete for nutrients and niche space. Therefore, bacteria
have to use different strategies to survive in the community, for example, by producing …