Human papillomaviruses: diversity, infection and host interactions
AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …
have co-evolved with their host to replicate in specific anatomical niches of the stratified …
[HTML][HTML] The papillomavirus E2 proteins
AA McBride - Virology, 2013 - Elsevier
The papillomavirus E2 proteins are pivotal to the viral life cycle and have well characterized
functions in transcriptional regulation, initiation of DNA replication and partitioning the viral …
functions in transcriptional regulation, initiation of DNA replication and partitioning the viral …
[HTML][HTML] Papillomavirus genome structure, expression, and post-transcriptional regulation
ZM Zheng, CC Baker - Frontiers in bioscience: a journal and virtual …, 2006 - ncbi.nlm.nih.gov
Papillomaviruses are a group of small non-enveloped DNA tumor viruses whose infection
usually causes benign epithelial lesions (warts). Certain types of HPVs, such as HPV-16 …
usually causes benign epithelial lesions (warts). Certain types of HPVs, such as HPV-16 …
Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.
H Romanczuk, PM Howley - Proceedings of the National …, 1992 - National Acad Sciences
The" high-risk" human papillomavirus types 16 (HPV-16) and 18 (HPV-18) have been
etiologically implicated in the majority of human cervical carcinomas. In these cancers, the …
etiologically implicated in the majority of human cervical carcinomas. In these cancers, the …
Human papillomavirus life cycle: active and latent phases
F Stubenrauch, LA Laimins - Seminars in cancer biology, 1999 - Elsevier
Productive infection by human papillomaviruses (HPV) is dependent upon the differentiation
of the host cell. Following entry into basal epithelial cells, HPV genomes are established as …
of the host cell. Following entry into basal epithelial cells, HPV genomes are established as …
Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator
IJ Mohr, R Clark, S Sun, EJ Androphy, P MacPherson… - Science, 1990 - science.org
The mechanism by which transcription factors stimulate DNA replication in eukaryotes is
unknown. Bovine papillomavirus DNA synthesis requires the products of the viral E1 gene …
unknown. Bovine papillomavirus DNA synthesis requires the products of the viral E1 gene …
Epigenetic regulation of human papillomavirus transcription in the productive virus life cycle
Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …
Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes
M Hummel, JB Hudson, LA Laimins - Journal of virology, 1992 - Am Soc Microbiol
The expression of viral genes during the productive life cycle of human papillomaviruses
(HPV) is tightly coupled to the differentiation program of epithelial cells. We have examined …
(HPV) is tightly coupled to the differentiation program of epithelial cells. We have examined …
Transient replication of BPV‐1 requires two viral polypeptides encoded by the E1 and E2 open reading frames.
M Ustav, A Stenlund - The EMBO journal, 1991 - embopress.org
Bovine papillomavirus (BPV) DNA is maintained as an episome with a constant copy
number in transformed cells and is stably inherited. To study BPV replication we have …
number in transformed cells and is stably inherited. To study BPV replication we have …
Transcriptional regulation of the human papillomavirus‐16 E6‐E7 promoter by a keratinocyte‐dependent enhancer, and by viral E2 trans‐activator and repressor …
TP Cripe, TH Haugen, JP Turk, F Tabatabai… - The EMBO …, 1987 - embopress.org
The transcriptional promoter of the candidate E6‐E7 transforming gene region of human
papillomavirus (HPV)‐16 (P97) was active in transiently transfected cervical carcinoma cells …
papillomavirus (HPV)‐16 (P97) was active in transiently transfected cervical carcinoma cells …