This review summarizes clinical studies in which glutathione was measured in tumor tissue
from patients with brain, breast, gastrointestinal, gynecological, head and neck and lung …

Metabolic phenotyping involves the comprehensive analysis of biological fluids or tissue
samples. This analysis allows biochemical classification of a person's physiological or …

The efficacy of standard glioblastoma (GBM) treatments has been limited due to the highly
immunosuppressive tumor immune microenvironment, interpatient tumor heterogenicity and …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

The investigation of metabolic pathways disturbed in isocitrate dehydrogenase (IDH) mutant
tumors revealed that the hallmark metabolic alteration is the production of D-2 …

Polymers that can change their properties in response to an external or internal stimulus
have become an interesting platform for drug delivery systems. Polymeric nanoparticles can …

Introduction: Depending in part on the glutathione: glutathione disulfide ratio, reversible
protein glutathionylation to a mixed disulfide may occur. Reversible glutathionylation is …

Despite advances in surgery and adjuvant therapy, brain tumors represent one of the
leading causes of cancer‐related mortality and morbidity in both adults and children …

The diagnosis of glioma is mainly based on imaging methods that do not distinguish
between stage and subtype prior to histopathological analysis. Patients with gliomas are …

Despite intensive research, brain tumors are amongst the malignancies with the worst
prognosis; therefore, a prompt diagnosis and thoughtful assessment of the disease is …