Human antimicrobial peptides and proteins
G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …
Designing improved active peptides for therapeutic approaches against infectious diseases
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
Convergent evolution of defensin sequence, structure and function
Defensins are a well-characterised group of small, disulphide-rich, cationic peptides that are
produced by essentially all eukaryotes and are highly diverse in their sequences and …
produced by essentially all eukaryotes and are highly diverse in their sequences and …
The defensins consist of two independent, convergent protein superfamilies
The defensin and defensin-like proteins are an extensive group of small, cationic, disulfide-
rich proteins found in animals, plants, and fungi and mostly perform roles in host defense …
rich proteins found in animals, plants, and fungi and mostly perform roles in host defense …
Antifungal peptides and proteins to control toxigenic fungi and mycotoxin biosynthesis
PV Martínez-Culebras, M Gandía, S Garrigues… - International Journal of …, 2021 - mdpi.com
The global challenge to prevent fungal spoilage and mycotoxin contamination on food and
feed requires the development of new antifungal strategies. Antimicrobial peptides and …
feed requires the development of new antifungal strategies. Antimicrobial peptides and …
Natural antimicrobial peptides as inspiration for design of a new generation antifungal compounds
M Bondaryk, M Staniszewska, P Zielińska… - Journal of fungi, 2017 - mdpi.com
Invasive fungal infections are associated with high mortality rates, despite appropriate
antifungal therapy. Limited therapeutic options, resistance development and the high …
antifungal therapy. Limited therapeutic options, resistance development and the high …
Novel formulations for antimicrobial peptides
AM Carmona-Ribeiro, LDM Carrasco - International journal of molecular …, 2014 - mdpi.com
Peptides in general hold much promise as a major ingredient in novel supramolecular
assemblies. They may become essential in vaccine design, antimicrobial chemotherapy …
assemblies. They may become essential in vaccine design, antimicrobial chemotherapy …
[HTML][HTML] Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
Hair follicles (HFs) function as hubs for stem cells, immune cells, and commensal microbes,
which must be tightly regulated during homeostasis and transient inflammation. Here we …
which must be tightly regulated during homeostasis and transient inflammation. Here we …
Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics
PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …
expected to continue to affect the population in forthcoming years. Additionally, treatment …
Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris
M Billamboz, Z Fatima, S Hameed, S Jawhara - Microorganisms, 2021 - mdpi.com
Invasive fungal infections represent an expanding threat to public health. During the past
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …