The E5 proteins are short transmembrane proteins encoded by many animal and human
papillomaviruses. These proteins display transforming activity in cultured cells and animals …

Papillomaviruses (PVs) are established agents of human and animal cancers. They infect
cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently …

Vascular pericytes, an important cellular component in the tumor microenvironment, are
often associated with tumor vasculatures, and their functions in cancer invasion and …

Bovine papillomaviruses (BPV) are DNA oncogenic viruses inducing hyperplastic benign
lesions of both cutaneous and mucosal epithelia in cattle. Ten (BPV 1-10) different viral …

The papillomavirus E5 proteins are short, hydrophobic transforming proteins. The
transmembrane E5 protein encoded by bovine papillomavirus transforms cells by activating …

Signalling molecules and pathways that mediate crosstalk between various tumour cellular
compartments in cancer metastasis remain largely unknown. We report a mechanism of the …

The TEL/PDGFβR fusion protein is the product of the t (5; 12) translocation in patients with
chronic myelomonocytic leukemia. The TEL/PDGFβR is an unusual fusion of a putative …

The E5 open reading frame of the human papillomavirus type 16 encodes a transmembrane
protein associated with the Golgi, ER, and plasma membranes. We have analyzed the effect …

Acquired mutations in the FLT3 receptor tyrosine kinase are common in acute myeloid
leukemia and result in constitutive activation. The most frequent mechanism of activation is …

Human papillomaviruses (HPVs) are strictly host-specific and also show a distinct tropism to
squamous epithelial cells. Upon HPV infection, only a portion of the virus reaching the …