lncRNA PVT1: a novel oncogene in multiple cancers

R Li, X Wang, C Zhu, K Wang - Cellular & molecular biology letters, 2022 - Springer
Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals

AC Palcau, V Canu, S Donzelli, S Strano, C Pulito… - Molecular Cancer, 2022 - Springer
The role of circular RNAs in oncogenesis has begun to be widely studied in recent years,
due to the significant impact that these molecules have in disease pathogenesis, as well as …

The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription

A Xia, W Yuan, Q Wang, J Xu, Y Gu, L Zhang, C Chen… - Nature cancer, 2022 - nature.com
Cancer-testis (CT) genes participate in the initiation and progression of cancer, but the role
of CT-associated long non-coding RNAs (CT-lncRNAs) in hepatocellular carcinoma (HCC) …

[HTML][HTML] Long noncoding RNA MAGI2-AS3 regulates the H2O2 level and cell senescence via HSPA8

Y Zhang, X Qiao, L Liu, W Han, Q Liu, Y Wang, T Xie… - Redox biology, 2022 - Elsevier
The redox homeostasis system regulates many biological processes, intracellular
antioxidant production and redox signaling. However, long noncoding RNAs (lncRNAs) …

Positive feedback regulation of lncRNA PVT1 and HIF2α contributes to clear cell renal cell carcinoma tumorigenesis and metastasis

M Zhang, L Zhang, L Fu, H Yao, L Tan, Z Feng, J Li… - Oncogene, 2021 - nature.com
Long noncoding RNAs (lncRNAs) have been reported to exert important roles in tumors,
including clear cell renal cell carcinoma (ccRCC). PVT1 is an important oncogenic lncRNA …

PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma

Z Qin, W Zhang, S Liu, Y Wang, X Peng, L Jia - Cell Death & Disease, 2023 - nature.com
Cancer stem cells (CSCs) cause tumor metastasis and immune evasion by as-yet-unknown
molecular mechanisms. In the present study, we identify a long noncoding RNA (lncRNA) …

Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology

SB Nukala, J Jousma, Y Cho, WH Lee, SG Ong - Cell & Bioscience, 2022 - Springer
Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …

[HTML][HTML] LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA

M Chen, R Zhang, L Lu, J Du, C Chen, K Ding… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Background: Numerous studies proved that long non-coding RNA (lncRNA) is involved in
the progression of multifarious diseases, especially in some carcinomas. As a potential …

Non-coding RNAs in ferroptotic cancer cell death pathway: meet the new masters

MR Valashedi, C Bamshad, N Najafi-Ghalehlou… - Human Cell, 2022 - Springer
Despite the recent advances in cancer therapy, cancer chemoresistance looms large along
with radioresistance, a major challenge in dire need of thorough and minute investigation …

Molecular mechanisms of lncRNAs in the dependent regulation of cancer and their potential therapeutic use

C García-Padilla, Á Dueñas, V García-López… - International Journal of …, 2022 - mdpi.com
Deep whole genome and transcriptome sequencing have highlighted the importance of an
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …