New horizons for precision medicine in biliary tract cancers

JW Valle, A Lamarca, L Goyal, J Barriuso, AX Zhu - Cancer discovery, 2017 - AACR
Biliary tract cancers (BTC), including cholangiocarcinoma and gallbladder cancer, are poor-
prognosis and low-incidence cancers, although the incidence of intrahepatic …

Current and emerging therapies for advanced biliary tract cancers

AE Kam, A Masood, RT Shroff - The lancet Gastroenterology & …, 2021 - thelancet.com
Biliary tract cancers (cholangiocarcinomas and gallbladder cancers) are increasing in
incidence and have a poor prognosis. Most patients present with advanced disease, for …

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

JW Valle, I Borbath, SA Khan, F Huguet… - Annals of …, 2016 - annalsofoncology.org
Biliary tract cancer (BTC), comprising< 1% of all human cancers and∼ 10%–15% of all
primary liver cancers, presents mostly in the seventh decade with a small male …

Gallbladder cancer in the 21st century

R Kanthan, JL Senger, S Ahmed… - Journal of …, 2015 - Wiley Online Library
Gallbladder cancer (GBC) is an uncommon disease in the majority of the world despite
being the most common and aggressive malignancy of the biliary tree. Early diagnosis is …

[HTML][HTML] Gallbladder cancer: expert consensus statement

TA Aloia, N Járufe, M Javle, SK Maithel, JC Roa… - Hpb, 2015 - Elsevier
Abstract An American Hepato-Pancreato-Biliary Association (AHPBA)-sponsored consensus
meeting of expert panellists was convened on 15 January 2014 to review current evidence …

Pathogenesis of cholangiocarcinoma

PM Rodrigues, P Olaizola, NA Paiva… - Annual Review of …, 2021 - annualreviews.org
Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …

Gemcitabine and oxaliplatin with or without cetuximab in advanced biliary-tract cancer (BINGO): a randomised, open-label, non-comparative phase 2 trial

D Malka, P Cervera, S Foulon, T Trarbach… - The lancet …, 2014 - thelancet.com
Background Gemcitabine plus a platinum-based agent (eg, cisplatin or oxaliplatin) is the
standard of care for advanced biliary cancers. We investigated the addition of cetuximab to …

Evaluation and management of intrahepatic and extrahepatic cholangiocarcinoma

NF Esnaola, JE Meyer, A Karachristos, JL Maranki… - Cancer, 2016 - Wiley Online Library
Cholangiocarcinomas are rare biliary tract tumors that are often challenging to diagnose and
treat. Cholangiocarcinomas are generally categorized as intrahepatic or extrahepatic …

Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study

J Lee, SH Park, HM Chang, JS Kim, HJ Choi… - The lancet …, 2012 - thelancet.com
Background Combination chemotherapy with gemcitabine and a platinum-based agent is
regarded as a standard treatment for patients with advanced biliary-tract cancer. Results of …

Gallbladder cancer: diagnosis, surgical management, and adjuvant therapies

L Hickman, C Contreras - Surgical Clinics, 2019 - surgical.theclinics.com
Gallbladder cancer (GBC) is a relatively rare occurrence with a poor prognosis (overall 5-
year survival is 50% for stage I cancers and 3% for stage IV cancers 1). Surgical resection is …