[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …
Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction
PC Westman, MJ Lipinski, D Luger, R Waksman… - Journal of the American …, 2016 - jacc.org
Abstract Treatment of acute myocardial infarction (AMI) has improved significantly in recent
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …
Targeting interleukin-1 in heart disease
Van Tassell et al IL-1 and Heart Disease 1911 progression of coronary artery disease and
impaired function. Nevertheless, reports of an inflammatory response during heart disease …
impaired function. Nevertheless, reports of an inflammatory response during heart disease …
Inflammatory networks in ageing, age-related diseases and longevity
Inflammation is considered a response set by the tissues in response to injury elicited by
trauma or infection. It is a complex network of molecular and cellular interactions that …
trauma or infection. It is a complex network of molecular and cellular interactions that …
Acute myocardial infarction
E Boersma, N Mercado, D Poldermans, M Gardien… - The Lancet, 2003 - thelancet.com
Acute myocardial infarction is a common disease with serious consequences in mortality,
morbidity, and cost to the society. Coronary atherosclerosis plays a pivotal part as the …
morbidity, and cost to the society. Coronary atherosclerosis plays a pivotal part as the …
Innate immunity and inflammation in ageing: a key for understanding age-related diseases
F Licastro, G Candore, D Lio, E Porcellini… - Immunity & …, 2005 - Springer
The process of maintaining life for the individual is a constant struggle to preserve his/her
integrity. This can come at a price when immunity is involved, namely systemic inflammation …
integrity. This can come at a price when immunity is involved, namely systemic inflammation …
Molecular, endocrine, and genetic mechanisms of arterial calcification
TM Doherty, LA Fitzpatrick, D Inoue, JH Qiao… - Endocrine …, 2004 - academic.oup.com
Pathologists have recognized arterial calcification for over a century. Recent years have
witnessed a strong resurgence of interest in atherosclerotic plaque calcification because it …
witnessed a strong resurgence of interest in atherosclerotic plaque calcification because it …
Transforming growth factor β and atherosclerosis: so far, so good for the protective cytokine hypothesis
DJ Grainger - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc
The role of the anti-inflammatory cytokine transforming growth factor β (TGF-β) in
atherosclerosis has been the subject of considerable debate for a decade. In the early …
atherosclerosis has been the subject of considerable debate for a decade. In the early …
Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction
L Zhou, A Azfer, J Niu, S Graham… - Circulation …, 2006 - Am Heart Assoc
Monocyte chemoattractant protein-1 (MCP-1; CCL2)–mediated inflammation plays a critical
role in the development of ischemic heart disease (IHD). However, the gene expression …
role in the development of ischemic heart disease (IHD). However, the gene expression …
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
ContextGiven the numerous, yet inconsistent, reports of genetic variants being associated
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …