Aptamer-based targeted delivery systems for cancer treatment using DNA origami and DNA nanostructures

A Jabbari, E Sameiyan, E Yaghoobi… - International Journal of …, 2023 - Elsevier
Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …

Recent advances in DNA origami-engineered nanomaterials and applications

P Zhan, A Peil, Q Jiang, D Wang, S Mousavi… - Chemical …, 2023 - ACS Publications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Polymeric Giant Unilamellar Vesicles with Integrated DNA‐Origami Nanopores: An Efficient Platform for Tuning Bioreaction Dynamics Through Controlled Molecular …

R Cochereau, V Maffeis, EC Dos Santos… - Advanced Functional …, 2023 - Wiley Online Library
Giant unilamellar vesicles (GUVs) are microcompartments serving to confine reactions,
allow signaling pathways, or design synthetic cells. Polymer GUVs are composed of …

Functional Nanopores Enabled with DNA

Y Xing, A Rottensteiner, J Ciccone… - Angewandte Chemie …, 2023 - Wiley Online Library
Membrane‐spanning nanopores are used in label‐free single‐molecule sensing and next‐
generation portable nucleic acid sequencing, and as powerful research tools in biology …

[HTML][HTML] Lipid vesicle-based molecular robots

Z Peng, S Iwabuchi, K Izumi, S Takiguchi, M Yamaji… - Lab on a Chip, 2024 - pubs.rsc.org
A molecular robot, which is a system comprised of one or more molecular machines and
computers, can execute sophisticated tasks in many fields that span from nanomedicine to …

[HTML][HTML] Diameter dependence of transport through nuclear pore complex mimics studied using optical nanopores

N Klughammer, A Barth, M Dekker, A Fragasso… - Elife, 2024 - elifesciences.org
The nuclear pore complex (NPC) regulates the selective transport of large biomolecules
through the nuclear envelope. As a model system for nuclear transport, we construct NPC …

The combination of DNA nanostructures and materials for highly sensitive electrochemical detection

R Tian, W Ma, L Wang, W Xie, Y Wang, Y Yin, T Weng… - …, 2024 - Elsevier
Due to the wide range of electrochemical devices available, DNA nanostructures and
material-based technologies have been greatly broadened. They have been actively used to …

Passing Behavior of Oligonucleotides through a Stacked DNA Nanochannel with Featured Path Design

R Zhang, Y Xiang, Y Yang - Journal of the American Chemical …, 2024 - ACS Publications
DNA nanotechnology has emerged as a useful tool for constructing artificial channels
penetrating the lipid bilayer. In this work, we introduce a stacked DNA origami nanochannel …

High spatial-resolved heat manipulating membrane heterogeneity alters cellular migration and signaling

X Chen, Q Yang, W Kong, Y Ge… - Proceedings of the …, 2023 - National Acad Sciences
Plasma membrane heterogeneity is a key biophysical regulatory principle of membrane
protein dynamics, which further influences downstream signal transduction. Although …

Compliant DNA Origami Nanoactuators as Size‐Selective Nanopores

Z Yu, AV Baptist, SCM Reinhardt, E Bertosin… - Advanced …, 2024 - Wiley Online Library
Biological nanopores crucially control the import and export of biomolecules across lipid
membranes in cells. They have found widespread use in biophysics and biotechnology …