Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Despite the capacity of chaperones and other homeostatic components to restore folding
equilibrium, cells appear poorly adapted for chronic oxidative stress that increases in cancer …

Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …

Heat shock proteins (Hsps) have been studied for many years and there is now a large body
of evidence that demonstrates the role of Hsp upregulation in tissue and cell protection in a …

• Introduction• Membrane lipid composition• Membrane lipid structure• Membrane lipid
organization‐Why so many different lipids?‐Lipid mixing and demixing‐Lateral pressure …

The 90 kDa heat shock proteins (Hsp90), which are integrally involved in cell signaling,
proliferation, and survival, are ubiquitously expressed in cells. Many proteins in tumor cells …

Maintenance of body temperature is achieved partly by modulating lipolysis by a network of
complex regulatory mechanisms. Lipolysis is an integral part of the glycerolipid/free fatty …

Autophagy is a central mechanism for maintaining cellular homeostasis in health and
disease as it provides the critical energy through the breakdown and recycling of cellular …

Ischemic tolerance describes the adaptive biological response of cells and organs that is
initiated by preconditioning (ie, exposure to stressor of mild severity) and the associated …

This study demonstrates the capability of multiwalled carbon nanotubes (MWNTs) coupled
with laser irradiation to enhance treatment of cancer cells through enhanced and more …