Mucosal vaccines, sterilizing immunity, and the future of SARS-CoV-2 virulence

D Focosi, F Maggi, A Casadevall - Viruses, 2022 - mdpi.com
Sterilizing immunity after vaccination is desirable to prevent the spread of infection from
vaccinees, which can be especially dangerous in hospital settings while managing frail …

Current and new rotavirus vaccines

RM Burke, JE Tate, CD Kirkwood… - Current opinion in …, 2019 - journals.lww.com
Rotavirus vaccines have demonstrated impact in reducing diarrheal morbidity and mortality
worldwide. As countries begin to introduce the newly prequalified vaccines, additional data …

Global burden and trends of rotavirus infection-associated deaths from 1990 to 2019: an observational trend study

Y Du, C Chen, X Zhang, D Yan, D Jiang, X Liu, M Yang… - Virology journal, 2022 - Springer
Background Rotavirus is the leading global pathogen of diarrhea-associated mortality and
poses a great threat to public health in all age groups. This study aimed to explore the global …

Rotavirus: Genetics, pathogenesis and vaccine advances

A Sadiq, N Bostan, KC Yinda… - Reviews in medical …, 2018 - Wiley Online Library
Since its discovery 40 years ago, rotavirus (RV) is considered to be a major cause of infant
and childhood morbidity and mortality particularly in developing countries. Nearly every …

Rotavirus vaccines: effectiveness, safety, and future directions

E Burnett, U Parashar, J Tate - Pediatric Drugs, 2018 - Springer
Rotavirus is the leading cause of diarrheal death among children< 5 years old worldwide,
estimated to have caused~ 215,000 deaths in 2013. Prior to rotavirus vaccine …

Rotavirus infection in children in Southeast Asia 2008–2018: disease burden, genotype distribution, seasonality, and vaccination

FB Lestari, S Vongpunsawad, N Wanlapakorn… - Journal of biomedical …, 2020 - Springer
Abstract Background Rotaviruses (RVs) are recognized as a major cause of acute
gastroenteritis (AGE) in infants and young children worldwide. Here we summarize the …

Efficacy of live oral rotavirus vaccines by duration of follow-up: a meta-regression of randomised controlled trials

A Clark, K van Zandvoort, S Flasche… - The Lancet Infectious …, 2019 - thelancet.com
Background The duration of protection offered by rotavirus vaccines varies across the world,
and this variation is important to understanding and predicting the effects of the vaccines …

Computational solutions of the HIV-1 infection of CD4+ T-cells fractional mathematical model that causes acquired immunodeficiency syndrome (AIDS) with the effect …

AH Abdel-Aty, MMA Khater, H Dutta, J Bouslimi… - Chaos, Solitons & …, 2020 - Elsevier
This paper investigates the exact traveling wave solutions of the fractional model of the
human immunodeficiency virus (HIV-1) infection for CD4+ T-cells. This model also treats …

The rotavirus vaccine story: from discovery to the eventual control of rotavirus disease

RI Glass, JE Tate, B Jiang… - The Journal of Infectious …, 2021 - academic.oup.com
Worldwide, rotavirus is the leading pathogen causing severe diarrhea in children and a
major cause of under 5 years mortality. In 1998, the first rotavirus vaccine, RotaShield, was …

Effect of rotavirus genetic diversity on vaccine impact

A Sadiq, N Bostan, J Khan… - Reviews in Medical …, 2022 - Wiley Online Library
Group A rotaviruses (RVAs) are the leading cause of gastroenteritis, causing 0.2 million
deaths and several million hospitalisations globally each year. Four rotavirus vaccines …