[HTML][HTML] Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling
Cellular homeostasis and adaptation to various environmental conditions are importantly
regulated by the sophisticated mechanism of autophagy and its crosstalk with Wnt signaling …
regulated by the sophisticated mechanism of autophagy and its crosstalk with Wnt signaling …
Cancer‐associated fibroblasts that restrain cancer progression: hypotheses and perspectives
The roles of cancer‐associated fibroblasts (CAF) in the progression of various types of
cancers are well established. CAF promote cancer progression through pleiotropic …
cancers are well established. CAF promote cancer progression through pleiotropic …
Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis
Y Mizutani, H Kobayashi, T Iida, N Asai, A Masamune… - Cancer research, 2019 - AACR
Cancer-associated fibroblasts (CAF) constitute a major component of the tumor
microenvironment. Recent observations in genetically engineered mouse models and …
microenvironment. Recent observations in genetically engineered mouse models and …
Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes
W Shengchen, L Jing, Y Yujie, W Yue… - Journal of hazardous …, 2021 - Elsevier
The environmental problem of Microplastics (MPs) pollution poses a great threat to human
and animal health, which has attracted global attention. The physiological integrity of …
and animal health, which has attracted global attention. The physiological integrity of …
[HTML][HTML] Selenoprotein K protects skeletal muscle from damage and is required for satellite cells-mediated myogenic differentiation
S Wang, X Zhao, Q Liu, Y Wang, S Li, S Xu - Redox biology, 2022 - Elsevier
The regeneration of adult skeletal muscle after injury is primarily initiated by satellite cells
(SCs), but the regulatory mechanisms of cells committed to myogenic differentiation remain …
(SCs), but the regulatory mechanisms of cells committed to myogenic differentiation remain …
Conductive self-healing biodegradable hydrogel based on hyaluronic acid-grafted-polyaniline as cell recruitment niches and cell delivery carrier for myogenic …
M Shi, R Dong, J Hu, B Guo - Chemical Engineering Journal, 2023 - Elsevier
Scaffold is one of the most important roles in skeletal muscle tissue engineering. Being
capable of mimicking extracellular matrix components, having electrical conductivity, and …
capable of mimicking extracellular matrix components, having electrical conductivity, and …
Pharmacologic conversion of cancer-associated fibroblasts from a protumor phenotype to an antitumor phenotype improves the sensitivity of pancreatic cancer to …
T Iida, Y Mizutani, N Esaki, SM Ponik, BM Burkel… - Oncogene, 2022 - nature.com
Previous therapeutic attempts to deplete cancer-associated fibroblasts (CAFs) or inhibit their
proliferation in pancreatic ductal adenocarcinoma (PDAC) were not successful in mice or …
proliferation in pancreatic ductal adenocarcinoma (PDAC) were not successful in mice or …
Autophagy in muscle regeneration: potential therapies for myopathies
W Chen, Y Chen, Y Liu, X Wang - Journal of Cachexia …, 2022 - Wiley Online Library
Autophagy classically functions as a physiological process to degrade cytoplasmic
components, protein aggregates, and/or organelles, as a mechanism for nutrient …
components, protein aggregates, and/or organelles, as a mechanism for nutrient …
[HTML][HTML] Roles of the mesenchymal stromal/stem cell marker Meflin/Islr in cancer fibrosis
M Takahashi, H Kobayashi, Y Mizutani… - Frontiers in Cell and …, 2021 - frontiersin.org
Fibroblasts synthesise the extracellular matrix (ECM) such as collagen and elastin, the
excessive accumulation of which can lead to fibrosis and organ dysfunction under …
excessive accumulation of which can lead to fibrosis and organ dysfunction under …
[HTML][HTML] LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma
Y Liu, S Li, S Wang, Q Yang, Z Wu, M Zhang… - International Journal of …, 2023 - nature.com
Cancer stem cell-like cells (CSCs) play an integral role in the heterogeneity, metastasis, and
treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high …
treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high …