Microglia are brain resident macrophages originated from primitive progenitor cells in the
yolk sac. Microglia can be activated within hours and recruited to the lesion site …

Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …

Abstract MicroRNA-124 (miR-124) is a brain specific miRNA that is highly expressed in
microglia. The upregulation of miR-124 contributes to M2 polarization of microglia, which is …

The essential roles of microglia in maintaining homeostasis in the healthy brain and
contributing to neuropathology are well documented. Emerging evidence suggests that …

Microglia, resident immune cells of the central nervous system, fulfill multiple functions in the
brain throughout life. These microglial functions range from participation in innate and …

It has recently emerged that microglia, the tissue-resident macrophages of the central
nervous system, play significant non-innate immune roles to support the development …

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder
affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous …

Microglia cells are the unique residential macrophages of the central nervous system (CNS).
They have a special origin, as they derive from the embryonic yolk sac and enter the …

Microglia, brain cells of nonneural origin, orchestrate the inflammatory response to diverse
insults, including hypoxia/ischemia or maternal/fetal infection in the perinatal brain …

Cocaine is known to activate microglia both in vitro and in vivo. High expression of microglial
Toll-like receptors (TLRs) and their downstream signal transducers play critical roles in …