[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
Metabolic interventions in the immune response to cancer
D O'Sullivan, DE Sanin, EJ Pearce… - Nature Reviews …, 2019 - nature.com
At the centre of the therapeutic dilemma posed by cancer is the question of how to develop
more effective treatments that discriminate between normal and cancerous tissues. Decades …
more effective treatments that discriminate between normal and cancerous tissues. Decades …
Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells
E Clement, I Lazar, C Attané, L Carrié… - The EMBO …, 2020 - embopress.org
Extracellular vesicles are emerging key actors in adipocyte communication. Notably, small
extracellular vesicles shed by adipocytes stimulate fatty acid oxidation and migration in …
extracellular vesicles shed by adipocytes stimulate fatty acid oxidation and migration in …
GDF-15 neutralization alleviates platinum-based chemotherapy-induced emesis, anorexia, and weight loss in mice and nonhuman primates
Platinum-based cancer therapy is restricted by dose-limiting side effects and is associated
with elevation of growth differentiation factor 15 (GDF-15). But whether this elevation …
with elevation of growth differentiation factor 15 (GDF-15). But whether this elevation …
Obesity and breast cancer: a case of inflamed adipose tissue
R Kolb, W Zhang - Cancers, 2020 - mdpi.com
Obesity is associated with an increased risk of estrogen receptor-positive breast cancer in
postmenopausal women and a worse prognosis for all major breast cancer subtypes …
postmenopausal women and a worse prognosis for all major breast cancer subtypes …
Hyperglycemia associated metabolic and molecular alterations in cancer risk, progression, treatment, and mortality
P Ramteke, A Deb, V Shepal, MK Bhat - Cancers, 2019 - mdpi.com
Cancer and diabetes are amongst the leading causes of deaths worldwide. There is an
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …
Lipid metabolism at the nexus of diet and tumor microenvironment
Obesity is a leading contributing factor to cancer development worldwide. Epidemiological
evidence suggests that diet affects cancer risk and also substantially alters therapeutic …
evidence suggests that diet affects cancer risk and also substantially alters therapeutic …
Effects of dietary zinc oxide nanoparticles supplementation on growth performance, zinc status, intestinal morphology, microflora population, and immune response in …
BACKGROUND This study evaluated the effects of dietary zinc oxide nanoparticles (nano‐
ZnOs) on growth performance, zinc status, intestinal morphology, microflora population, and …
ZnOs) on growth performance, zinc status, intestinal morphology, microflora population, and …
Emerging roles of lipid metabolism in cancer progression
To proliferate, metastasize, or resist stress conditions imposed by the microenvironment,
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …
many cancer cells rely on fatty acid β-oxidation to generate acetyl-CoA and fuel the TCA …
[HTML][HTML] Lysine restriction affects feed intake and amino acid metabolism via gut microbiome in piglets
Background/Aims: Our previous reports suggested that dietary supplementation with lysine
influenced intestinal absorption and metabolism of amino acids. In this study, we further …
influenced intestinal absorption and metabolism of amino acids. In this study, we further …