Blood flow in the microcirculation

TW Secomb - Annual Review of Fluid Mechanics, 2017 - annualreviews.org
The microcirculation is an extensive network of microvessels that distributes blood flow
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …

The structure and function of the endothelial glycocalyx layer

S Weinbaum, JM Tarbell… - Annu. Rev. Biomed. Eng …, 2007 - annualreviews.org
Over the past decade, since it was first observed in vivo, there has been an explosion in
interest in the thin (∼ 500 nm), gel-like endothelial glycocalyx layer (EGL) that coats the …

The endothelial surface layer

AR Pries, TW Secomb, P Gaehtgens - Pflügers Archiv, 2000 - Springer
The endothelial lining of blood vessels presents a large surface area for exchange of
materials between blood and tissues, and is critically involved in many other processes such …

Self-shrinking soft demoulding for complex high-aspect-ratio microchannels

D Fan, X Yuan, W Wu, R Zhu, X Yang, Y Liao… - Nature …, 2022 - nature.com
Microchannels are the essential elements in animals, plants, and various artificial devices
such as soft robotics, wearable sensors, and organs-on-a-chip. However, three-dimensional …

Microcirculation and hemorheology

AS Popel, PC Johnson - Annu. Rev. Fluid Mech., 2005 - annualreviews.org
▪ Abstract We review major experimental and theoretical studies on microcirculation and
hemorheology, focusing on mechanics of blood flow and the vascular wall. We discuss flow …

Precapillary sphincters maintain perfusion in the cerebral cortex

S Grubb, C Cai, BO Hald, L Khennouf… - Nature …, 2020 - nature.com
Active nerve cells release vasodilators that increase their energy supply by dilating local
blood vessels, a mechanism termed neurovascular coupling and the basis of BOLD …

[图书][B] Snapshots of hemodynamics: an aid for clinical research and graduate education

N Westerhof, N Stergiopulos, MIM Noble, BE Westerhof - 2018 - books.google.com
This book is written in a quick reference style to help clinical and basic researchers, as well
as graduate students, in the understanding of hemodynamics. Recent dev-opments in …

Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain

F Fernández-Klett, N Offenhauser… - Proceedings of the …, 2010 - National Acad Sciences
Modern functional imaging techniques of the brain measure local hemodynamic responses
evoked by neuronal activity. Capillary pericytes recently were suggested to mediate …

Biophysical aspects of blood flow in the microvasculature

AR Pries, TW Secomb, P Gaehtgens - Cardiovascular research, 1996 - academic.oup.com
The main function of the microvasculature is transport of materials. Water and solutes are
carried by blood through the microvessels and exchanged, through vessel walls, with the …

Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries

H Vink, BR Duling - Circulation research, 1996 - Am Heart Assoc
A thick endothelial surface coat consisting of the glycocalyx and associated plasma proteins
has been hypothesized to reduce functional capillary volume available for flowing plasma …