Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies

YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

V Ratushny, MD Gober, R Hick… - The Journal of …, 2012 - Am Soc Clin Investig
Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer
with over 250,000 new cases annually in the US and is second in incidence only to basal …

Epithelial stem cells, wound healing and cancer

EN Arwert, E Hoste, FM Watt - Nature Reviews Cancer, 2012 - nature.com
It is well established that tissue repair depends on stem cells and that chronic wounds
predispose to tumour formation. However, the association between stem cells, wound …

Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair

AM Hocking, NS Gibran - Experimental cell research, 2010 - Elsevier
Cutaneous wounds persist as a health care crisis in spite of increased understanding of the
cellular and molecular responses to injury. Contributing significantly to this crisis is the lack …

Cardiac stem cells and mechanisms of myocardial regeneration

A Leri, JAN Kajstura, P Anversa - Physiological reviews, 2005 - journals.physiology.org
This review discusses current understanding of the role that endogenous and exogenous
progenitor cells may have in the treatment of the diseased heart. In the last several years, a …

Bone marrow‐derived stem cells in wound healing: a review

Y Wu, JF Wang, PG Scott… - Wound Repair and …, 2007 - Wiley Online Library
Optimum healing of a cutaneous wound requires a well‐orchestrated integration of the
complex biological and molecular events of cell migration and proliferation, and of …

Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration

Y Wu, RCH Zhao, EE Tredget - Stem cells, 2010 - academic.oup.com
Our understanding of the role of bone marrow (BM)-derived cells in cutaneous homeostasis
and wound healing had long been limited to the contribution of inflammatory cells. Recent …

Cell recruiting chemokine-loaded sprayable gelatin hydrogel dressings for diabetic wound healing

DS Yoon, Y Lee, HA Ryu, Y Jang, KM Lee, Y Choi… - Acta biomaterialia, 2016 - Elsevier
In this study, we developed horseradish peroxidase (HRP)-catalyzed sprayable gelatin
hydrogels (GH) as a bioactive wound dressing that can deliver cell-attracting chemotactic …

Epithelial stem cells and implications for wound repair

MV Plikus, DL Gay, E Treffeisen, A Wang… - Seminars in cell & …, 2012 - Elsevier
Activation of epithelial stem cells and efficient recruitment of their proliferating progeny plays
a critical role in cutaneous wound healing. The reepithelialized wound epidermis has a …

The gastrointestinal tract stem cell niche

TH Yen, NA Wright - Stem cell reviews, 2006 - Springer
The gastrointestinal epithelium is unique in that cell proliferation, differentiation, and
apoptosis occur in an orderly fashion along the crypt-villus axis. The intestinal crypt is mainly …