Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …

Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …

Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Zika virus (ZIKV) belongs to the family Flaviviridae, and is related to other viruses that cause
human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological …

Epidemiological synergy between outbreaks of viruses transmitted by Aedes aegypti
mosquitoes, such as chikungunya, dengue, and Zika viruses, has resulted in coinfection of …

The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

Dengue virus (DENV) infection can result in severe complications. However, the
understanding of the molecular correlates of severity is limited, partly due to difficulties in …

Macrophages represent one of the most numerous and diverse leukocyte types in the body.
Furthermore, they are important regulators and promoters of many cardiovascular disease …

Monoclonal antibody (mAb) therapeutics are an effective modality for the treatment of
infectious, autoimmune, and cancer-related diseases. However, the discovery, development …