Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

CC Barron, PJ Bilan, T Tsakiridis, E Tsiani - Metabolism, 2016 - Elsevier
It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

Concise review: prostate cancer stem cells: current understanding

S Skvortsov, II Skvortsova, DG Tang, A Dubrovska - Stem Cells, 2018 - academic.oup.com
Prostate cancer (PCa) is heterogeneous, harboring phenotypically diverse cancer cell types.
PCa cell heterogeneity is caused by genomic instability that leads to the clonal competition …

GLUT1 regulates cell glycolysis and proliferation in prostate cancer

H Xiao, J Wang, W Yan, Y Cui, Z Chen, X Gao… - The …, 2018 - Wiley Online Library
Background Glucose transporter 1 (GLUT1) plays a critical role in tumorigenesis and tumor
progression in multiple cancer types. However, the specific function and clinical significance …

Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for 18F-FDG …

MK Bakht, JM Lovnicki, J Tubman… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Although the incidence of de novo neuroendocrine prostate cancer (PC) is rare, recent data
suggest that low expression of prostate-specific membrane antigen (PSMA) is associated …

Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death

E de Alteriis, F Cartenì, P Parascandola, J Serpa… - Cell Cycle, 2018 - Taylor & Francis
The mechanisms behind the Warburg effect in mammalian cells, as well as for the similar
Crabtree effect in the yeast Saccharomyces cerevisiae, are still a matter of debate: why do …

Immune response of silver pomfret (Pampus argenteus) to Amyloodinium ocellatum infection

Y Zhang, J Hu, Y Li, M Zhang, KJ Jacques… - Journal of Fish …, 2021 - Wiley Online Library
Amyloodinium ocellatum (AO) infection in silver pomfret (Pampus argenteus) causes
extensive mortality. Insufficient information exists on the molecular immune response of …

GLUT1 is an AR target contributing to tumor growth and glycolysis in castration-resistant and enzalutamide-resistant prostate cancers

J Wang, W Xu, B Wang, G Lin, Y Wei, M Abudurexiti… - Cancer Letters, 2020 - Elsevier
Castration-resistant prostate cancer (CRPC) displays a higher 18 F-FDG PET SUV max than
hormone-sensitive prostate cancer, which suggests a greater need for glucose metabolism …

The Evolving Role of 18F-FDG PET/CT in Diagnosis and Prognosis Prediction in Progressive Prostate Cancer

K Shen, B Liu, X Zhou, Y Ji, L Chen, Q Wang… - Frontiers in …, 2021 - frontiersin.org
Positron emission tomography/computed tomography (PET/CT) is widely used in prostate
cancer to evaluate the localized tumor burden and detect symptomatic metastatic lesions …

[HTML][HTML] GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress

P Gonzalez-Menendez, D Hevia, R Alonso-Arias… - Redox biology, 2018 - Elsevier
Glucose, chief metabolic support for cancer cell survival and growth, is mainly imported into
cells by facilitated glucose transporters (GLUTs). The increase in glucose uptake along with …

Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression

J Lazniewska, KL Li, IRD Johnson, A Sorvina… - Scientific reports, 2023 - nature.com
Prostate cancer (PCa) development and progression relies on the programming of glucose
and lipid metabolism, and this involves alterations in androgen receptor expression and …