[HTML][HTML] Experimental models of fatty liver diseases: Status and appraisal

H Wang, H Shen, W Seo, S Hwang - Hepatology Communications, 2023 - journals.lww.com
Fatty liver diseases, including alcohol-associated liver disease (ALD) and nonalcoholic fatty
liver disease nonalcoholic fatty liver disease (NAFLD), affect a large number of people …

[HTML][HTML] COVID-19, Possible Hepatic Pathways and Alcohol Abuse—What Do We Know up to 2023?

A Michalak, T Lach, K Szczygieł… - International Journal of …, 2024 - mdpi.com
The pandemic period due to coronavirus disease 2019 (COVID-19) revolutionized all
possible areas of global health. Significant consequences were also related to diverse …

Mechanism of the Effect of Compound Anoectochilus roxburghii (Wall.) Lindl. Oral Liquid in Treating Alcoholic Rat Liver Injury by Metabolomics

T Huang, Y Wu, L Huang, R Lin, Z Li… - Drug Design …, 2023 - Taylor & Francis
Purpose Compound Anoectochilus roxburghii (Wall.) Lin dl oral liquid (CAROL) is often as a
hepatoprotective agent. The present study aimed to elucidate the protective mechanism of …

[HTML][HTML] Walnut (Juglans regia L.) Oligopeptides Alleviate Alcohol-Induced Acute Liver Injury through the Inhibition of Inflammation and Oxidative Stress in Rats

R Liu, YT Hao, N Zhu, XR Liu, RX Mao, JW Kang… - Nutrients, 2023 - mdpi.com
The study was aimed at investigating the effects of walnut oligopeptides (WOPs) on alcohol-
induced acute liver injury and its underlying mechanisms. Male Sprague Dawley (SD) rats …

[HTML][HTML] Apple consumption protects against acute ethanol-induced liver injury in rats

C Wang, CN Ma, XL Liu, Q Sun, Q Zhang, YY Lin… - Applied sciences, 2023 - mdpi.com
Acute alcoholic liver injury is an important health problem worldwide. Apples are rich in
many nutrients and have a variety of biological activities, including antioxidant, anti …

Bruceine A alleviates alcoholic liver disease by inhibiting AIM2 inflammasome activation via activating FXR

L Li, S Xu, W Wang, X Li, H Wang, Q Yang, C Wang… - Phytomedicine, 2024 - Elsevier
Background Alcoholic liver disease (ALD), a public health challenge worldwide caused by
long-term persistent drinking, is life-threatening with minimal approved therapies. Hepatic …

[HTML][HTML] Phosphoglycerate mutase 5 aggravates alcoholic liver disease through disrupting VDAC-1-dependent mitochondrial integrity

T Xia, J Yu, Y Chen, X Chang… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) poses a substantial global health challenge, with its
pathogenesis deeply rooted in mitochondrial dysfunction. Our study explores the pivotal …

[HTML][HTML] Pharmacological inhibition of the Src homology phosphatase 2 confers partial protection in a mouse model of alcohol-associated liver disease

MF Hsu, S Koike, CS Chen, SM Najjar, TC Meng… - Biomedicine & …, 2024 - Elsevier
Alcohol-associated liver disease (ALD) is a leading factor of liver-related death worldwide.
ALD has various manifestations that include steatosis, hepatitis, and cirrhosis and is …

ENPP2/Autotaxin: The potential drug target for alcoholic liver disease identified through Mendelian randomization analysis

P Luo, X Yu - Liver International, 2024 - Wiley Online Library
Abstract Background and Aims At present, there is still a lack of radical drug targets for
intervention in alcoholic liver disease (ALD), and drug discovery through randomized …

[HTML][HTML] Regulation Mechanism and Potential Value of Active Substances in Spices in Alcohol–Liver–Intestine Axis Health

J Huang, T Huang, J Li - International Journal of Molecular Sciences, 2024 - mdpi.com
Excessive alcohol intake will aggravate the health risk between the liver and intestine and
affect the multi-directional information exchange of metabolites between host cells and …