The neurotransmitters GABA and glycine mediate fast synaptic inhibition by activating ligand-
gated chloride channels—namely, type A GABA (GABAA) and glycine receptors. Both types …

GABA (γ-aminobutyric acid) type A receptors (GABAARs) mediate most fast synaptic
inhibition in the mammalian brain, controlling activity at both the network and the cellular …

Advances in super-resolution microscopy have demonstrated single-molecule localization
precisions of a few nanometers. However, translation of such high localization precisions …

Proper developmental, neural cell-type-specific, and activity-dependent regulation of
GABAergic transmission is essential for virtually all aspects of CNS function. The number of …

In the mammalian CNS, each neuron typically receives thousands of synaptic inputs from
diverse classes of neurons. Synaptic transmission to the postsynaptic neuron relies on …

Older concepts of a hard-wired adult brain have been overturned in recent years by in vivo
imaging studies revealing synaptic remodeling, now thought to mediate rearrangements in …

Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …

Inflammation has been implicated in the progression of neurological disease, yet precisely
how inflammation affects neuronal function remains unclear. Tumor necrosis factor-α (TNFα) …

Repetitive transcranial magnetic stimulation (rTMS) is used as a therapeutic tool in
neurology and psychiatry. While repetitive magnetic stimulation (rMS) has been shown to …

Inhibitory synapses mediate the majority of synaptic inhibition in the brain, thereby
controlling neuronal excitability, firing, and plasticity. Although essential for neuronal …