Abstract Background &Aims: Thiamine is an essential micronutrient for energy metabolism.
Thiamine deficiency is frequently observed in critically ill patients. However, the effect of …

Introduction: This systematic review aimed to assess the efficacy and safety of
hydrocortisone, ascorbic acid, and thiamine (HAT) combination therapy in patients with …

Multi-organ dysfunction is a major issue in critically ill patients, where a significant
inflammatory response appears to be the primary factor driving the degree of organ …

Despite significant progress in our understanding of the pathophysiology of sepsis and
extensive clinical research, there are few proven therapies addressing the underlying …

There has been increasing interest in the role of micronutrient supplementation in critical
care. This narrative review summarizes the recent studies on micronutrients in critically ill …

Sepsis, characterized by life-threatening organ dysfunction due to a maladaptive host
response to infection, and its more severe form, septic shock, pose significant global health …

Background and Objectives: According to the Third International Consensus Definitions for
Sepsis and Septic Shock (Sepsis-3), sepsis is defined as “life-threatening organ dysfunction …

The multifaceted role of vitamin C, also known as ascorbic acid, in cellular homeostasis has
been underscored, with particular emphasis on its involvement as a co-factor in crucial …

Abstract Systematic Inflammatory Response Syndrome and Sepsis are inflammatory
responses to many health manifestations. Sepsis mortality is high despite global treatment …

Askorbik asit olarak da bilinen C vitamininin hücresel homeostazdaki çok yönlü rolü,
özellikle önemli hidroksilasyon reaksiyonlarında yardımcı bir faktör olarak rol oynaması …