[HTML][HTML] Recent findings on the impact of ErbB receptors status on prognosis and therapy of head and neck squamous cell carcinoma

C Palumbo, M Benvenuto, C Focaccetti… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type,
has often an aggressive course and is poorly responsive to current therapeutic approaches …

[HTML][HTML] Nuclear epidermal growth factor receptor as a therapeutic target

B Atwell, P Chalasani, J Schroeder - Exploration of Targeted Anti …, 2023 - ncbi.nlm.nih.gov
Epidermal growth factor receptor (EGFR) is one of the most well-studied oncogenes with
roles in proliferation, growth, metastasis, and therapeutic resistance. This intense study has …

[HTML][HTML] Nuclear epidermal growth factor receptor overexpression as a survival predictor in oral squamous cell carcinoma

M Tarle, M Raguž, D Muller, I Lukšić - International journal of molecular …, 2023 - mdpi.com
The aim of this study was to determine, by immunohistochemical methods, the expression of
nEGFR and markers of cell proliferation (Ki-67), cell cycle (mEGFR, p53, cyclin D1), and …

New phthalimide-based derivatives as EGFR-TK inhibitors: Synthesis, biological evaluation, and molecular modeling study

NI Mansour, SM El-Sayed, NS El-Gohary… - Bioorganic …, 2022 - Elsevier
A novel series of phthalimide derivatives was synthesized and evaluated for in vitro
antitumor activity against six human cancer cell lines; HepG-2, HCT-116, MCF-7, Hep2, PC3 …

[HTML][HTML] Long-Term Care and Follow-Up in Laryngeal Cancer Patients: A Multicenter Retrospective Analysis

B Marijić, F Tudor, S Janik, S Grasl, F Frommlet… - Journal of Personalized …, 2023 - mdpi.com
Purpose: We conducted an outcome analysis on surgically treated laryngeal squamous cell
carcinoma (LSCC) patients. Methods: A multicenter retrospective study with 352 patients …

[HTML][HTML] IMP3 protein overexpression is linked to unfavorable outcome in laryngeal squamous cell carcinoma

D Maržić, B Marijić, T Braut, S Janik, M Avirović… - Cancers, 2021 - mdpi.com
Simple Summary IMP3 expression was analyzed in patients with malignant (laryngeal
squamous cell carcinoma), semi-malignant (dysplasia) and benign (nodules, polyps) …

Significance of nuclear EGFR and ABCG2 expression in malignant transformation of oral potentially malignant disorders

M Tarle, D Müller, M Raguž, I Lukšić - Head & Neck, 2022 - Wiley Online Library
Background The purpose of this study was to investigate the expression of nuclear EGFR
(nEGFR) and the stem cell marker ABCG2 in oral leukoplakia (OL) and oral erythroplakia …

Izraženost jezgrina receptora epidermalnog čimbenika rasta kao biljega u premalignim i malignim promjenama usne šupljine

M Tarle - 2023 - repozitorij.mef.unizg.hr
Cilj: Glavni cilj ovog istraživanja bio je imunohistokemijskim metodama iz uzoraka oralnih
leukoplakija (OL) i eritroplakija (OE) te planocelularnih karcinoma usne šupljine (OSCC) …