ARF1 compartments direct cargo flow via maturation into recycling endosomes

A Stockhammer, P Adarska, V Natalia, A Heuhsen… - Nature Cell …, 2024 - nature.com
Cellular membrane homoeostasis is maintained via a tightly regulated membrane and cargo
flow between organelles of the endocytic and secretory pathways. Adaptor protein …

Distinct trafficking routes of polarized and non-polarized membrane cargoes in Aspergillus nidulans

GM Sagia, X Georgiou, G Chamilos, G Diallinas… - eLife, 2024 - elifesciences.org
Membrane proteins are sorted to the plasma membrane via Golgi-dependent trafficking.
However, our recent studies challenged the essentiality of Golgi in the biogenesis of specific …

Disordered hinge regions of the AP-3 adaptor complex promote vesicle budding from the late Golgi in yeast

M Leih, RL Plemel, M West, CG Angers… - Journal of Cell …, 2024 - journals.biologists.com
Vesicles bud from maturing Golgi cisternae in a programmed sequence. Budding is
mediated by adaptors that recruit cargoes and facilitate vesicle biogenesis. In …

Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis

V Szentgyörgyi, LM Lueck, D Overwijn, D Ritz… - Journal of Cell …, 2024 - rupress.org
Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome
homeostasis | Journal of Cell Biology | Rockefeller University Press Skip to Main Content …

Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation

A Khakurel, I Pokrovskaya, V Lupashin - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
The GARP complex is an evolutionarily conserved protein complex proposed to tether
endosome-derived vesicles at the trans-Golgi network. While prolonged depletion of GARP …

[引用][C] Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake

KV Kandror - 2024 - Elsevier