Voltage-gated calcium (Cav) channels serve dual roles in the cell, where they can both
depolarize the membrane potential for electrical excitability, and activate transient …

Voltage-gated calcium channels (VGCCs) represent a key link between electrical signals
and non-electrical processes, such as contraction, secretion and transcription. Evolved to …

C. elegans neuronal system constitutes the ideal framework for studying simple, yet realistic,
neuronal activity, since the whole nervous system is fully characterized with respect to the …

High-frequency" burst" clusters of spikes are a generic output pattern of many neurons.
While bursting is a ubiquitous computational feature of different nervous systems across …

Intracellular Ca2+ transient is crucial in initiating the differentiation of mesenchymal cells into
chondrocytes, but whether voltage-gated Ca2+ channels are involved remains uncertain …

Among the annelids, earthworms are renowned for their phenomenal ability to regenerate
the lost segments. The adult earthworm Eudrilus eugeniae contains 120 segments and the …

Four-domain voltage-gated Ca2+ (Cav) channels play fundamental roles in the nervous
system, but little is known about when or how their unique properties and cellular roles …

Among the rare venomous mammals, the short-tailed shrew Blarina brevicauda has been
suggested to produce potent neurotoxins in its saliva to effectively capture prey. Several …

Ca V 1 and Ca V 2 voltage-gated calcium channels evolved from an ancestral Ca V 1/2
channel via gene duplication somewhere near the stem animal lineage. The divergence of …

Background Ca v 3.2 is a T‐type calcium channel that causes low‐threshold exocytosis. T‐
type calcium channel blockers reduce platelet granule exocytosis and aggregation …