Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …

(1) Background: Dyes play an important role in food, medicine, textile, and other industries,
which make human life more colorful. With the increasing demand for food safety, the …

Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in
2018 and a sustained rise in its incidence in both developing and developed countries …

Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

Chemoresistance and development of relapses are ascribable to a rare cell population of
tumour mass: cancer stem cells (CSCs). Targeting CSCs could increase patients' survival …

Saffron, a Crocus sativus L. derivative, has been recognized for its medical benefits since
ancient times. Besides being an active flavoring and coloring agent in several food items …

Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

The Wnt/β-catenin signaling pathway is an evolutionarily conserved developmental
signaling event that plays a critical role in regulating tissue development and maintaining …

Metastasis represents a major obstacle in cancer treatment and the leading cause of cancer-
related deaths. Therefore, the identification of compounds targeting the multi-step and …

Saffron is located in the upper part of the crocus stigma of iridaceae, which has a long
history of medicinal use. Crocin (molecular formula C 44 H 64 O 24) is a natural floral …