Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …

Fluorine compounds are known for their abundance in more than 20% of pharmaceutical
and agrochemical products mainly due to the enhanced lipophilicity, metabolic stability and …

Key similarities and differences of Pd and Ni in catalytic systems are discussed. Overall, Ni
and Pd catalyze a vast number of similar C–C and C–heteroatom bond-forming reactions …

We disclose a Bi-catalyzed C–H trifluoromethylation of (hetero) arenes using CF3SO2Cl
under light irradiation. The catalytic method permits the direct functionalization of various …

The application of piezoelectricity for the generation of trifluoromethyl (CF3) radicals is
reported together with the development of a method for the mechanochemical C− H …

Herein, we report a reaction that selectively generates 3-arylpyridine and quinoline motifs by
inserting aryl carbynyl cation equivalents into pyrrole and indole cores, respectively. By …

Owing to the market competitiveness and urgent societal need, an optimum speed of drug
discovery is an important criterion for successful implementation. Despite the rapid ascent of …

The synthesis of small organic molecules with a difluoromethylated stereocenter is
particularly attractive in drug discovery. Herein, we have developed an efficient method for …

A cobalt photocatalyst for direct trifluoromethylation of (hetero) arene C (sp2)–H bonds is
described and shown to operate via visible light activation of a Co–CF3 intermediate, which …

Visible‐light‐photocatalyzed methods employed in synthetic transformations present
attractive properties such as environmentally friendly, safety, availability and excellent …