Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

RNA therapeutics have the potential to resolve a myriad of genetic diseases. Lipid
nanoparticles (LNPs) are among the most successful RNA delivery systems. Expanding their …

G-protein-coupled receptors (GPCRs) mediate many critical physiological processes. Their
spatial organization in plasma membrane (PM) domains is believed to encode signaling …

Lipid bilayers can exhibit asymmetric states, in which the physical characteristics of one
leaflet differ from those of the other. This most visibly manifests in a different lipid …

Many biological processes involve large-scale changes in membrane shape. Computer
simulations of these processes are challenging since they occur across a wide range of …

Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

Many plasma membrane (PM) functions depend on the cholesterol concentration in the PM
in strikingly nonlinear, cooperative ways: fully functional in the presence of physiological …

In the field of bottom‐up synthetic biology, lipid vesicles provide an important role in the
construction of artificial cells. Giant unilamellar vesicles (GUVs), due to their membrane's …

Biological membranes exhibit diversity in their shapes and complexity in chemical
compositions that are linked to many cellular functions. These two central features of …