Sixty years of amphotericin B: an overview of the main antifungal agent used to treat invasive fungal infections
FB Cavassin, JL Baú-Carneiro, RR Vilas-Boas… - Infectious Diseases and …, 2021 - Springer
Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …
discovery of amphotericin B and its therapeutic uses is considered one of the most important …
Nanoemulsion: Concepts, development and applications in drug delivery
Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents
Many deadly infections are produced by microorganisms capable of sustained survival in
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …
Applications of nanomaterials in leishmaniasis: a focus on recent advances and challenges
Leishmaniasis is a widely distributed protozoan vector-born disease affecting almost 350
million people. Initially, chemotherapeutic drugs were employed for leishmania treatment but …
million people. Initially, chemotherapeutic drugs were employed for leishmania treatment but …
Recent developments and future prospects in the treatment of visceral leishmaniasis
Limited therapeutic options in visceral leishmaniasis (VL) make the treatment of this
neglected disease very challenging. In addition to this, long treatment duration and toxic …
neglected disease very challenging. In addition to this, long treatment duration and toxic …
Phloretin loaded chitosan nanoparticles augments the pH-dependent mitochondrial-mediated intrinsic apoptosis in human oral cancer cells
AVA Mariadoss, R Vinayagam, V Senthilkumar… - International journal of …, 2019 - Elsevier
The aim of the present investigation is to explore the innovative platform for the synthesis of
plant-based nanoparticles, which contain biocompatible and biodegradable carrier of …
plant-based nanoparticles, which contain biocompatible and biodegradable carrier of …
Nanostructured delivery systems with improved leishmanicidal activity: a critical review
N Bruni, B Stella, L Giraudo, C Della Pepa… - International journal …, 2017 - Taylor & Francis
Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …
genus Leishmania, which are responsible for numerous clinical manifestations, such as …
Activity of amphotericin B-loaded chitosan nanoparticles against experimental cutaneous leishmaniasis
Chitosan nanoparticles have gained attention as drug delivery systems (DDS) in the medical
field as they are both biodegradable and biocompatible with reported antimicrobial and anti …
field as they are both biodegradable and biocompatible with reported antimicrobial and anti …
Characterization and evaluation of amphotericin B loaded MDP conjugated poly (propylene imine) dendrimers
This paper describes a novel strategy for targeted delivery of amphotericin B (AmB) to
macrophages with muramyl dipeptide (MDP) conjugated multimeric poly …
macrophages with muramyl dipeptide (MDP) conjugated multimeric poly …
Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis
Aim: Our goal was to improve treatment outcomes for visceral leishmaniasis by designing
nanocarriers that improve drug biodistribution and half-life. Thus, long-acting mannose …
nanocarriers that improve drug biodistribution and half-life. Thus, long-acting mannose …