[HTML][HTML] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …

[HTML][HTML] Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention

E Shirbhate, J Pandey, VK Patel, M Kamal… - Pharmacological …, 2021 - Springer
Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …

[HTML][HTML] The SARS-CoV-2 spike glycoprotein as a drug and vaccine target: structural insights into its complexes with ACE2 and antibodies

AC Papageorgiou, I Mohsin - Cells, 2020 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of
the Coronavirus disease (COVID-19) pandemic, has so far resulted in more than 1.1 M …

[HTML][HTML] An effective MM/GBSA protocol for absolute binding free energy calculations: A case study on SARS-CoV-2 spike protein and the human ACE2 receptor

N Forouzesh, N Mishra - Molecules, 2021 - mdpi.com
The binding free energy calculation of protein–ligand complexes is necessary for research
into virus–host interactions and the relevant applications in drug discovery. However, many …

Multiple routes of antibody-dependent enhancement of SARS-CoV-2 infection

K Okuya, T Hattori, T Saito, Y Takadate… - Microbiology …, 2022 - Am Soc Microbiol
Antibody-dependent enhancement (ADE) of infection is generally known for many viruses. A
potential risk of ADE in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: modeling and simulation approaches

A Frances-Monerris, C Hognon, T Miclot… - Journal of Proteome …, 2020 - ACS Publications
The emergence in late 2019 of the coronavirus SARS-CoV-2 has resulted in the
breakthrough of the COVID-19 pandemic that is presently affecting a growing number of …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Electrostatic features for the receptor binding domain of SARS-COV-2 wildtype and its variants. Compass to the severity of the future variants with the charge-rule

FL Barroso da Silva, CC Giron… - The Journal of Physical …, 2022 - ACS Publications
Electrostatic intermolecular interactions are important in many aspects of biology. We have
studied the main electrostatic features involved in the interaction of the receptor-binding …

[HTML][HTML] Peptide epitope-imprinted polymer microarrays for selective protein recognition. Application for SARS-CoV-2 RBD protein

Z Bognár, E Supala, A Yarman, X Zhang, FF Bier… - Chemical …, 2022 - pubs.rsc.org
We introduce a practically generic approach for the generation of epitope-imprinted polymer-
based microarrays for protein recognition on surface plasmon resonance imaging (SPRi) …

SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral …

Z Wang, J Zhou, B Marshall, R Rekaya… - ACS pharmacology & …, 2020 - ACS Publications
As a result of the COVID-19 pandemic, evidence revealed that SARS-CoV-2 infection
caused taste loss at a rate higher than that of influenza. ACE2, the entry receptor of SARS …