A meta-analysis on progressive atrophy in intractable temporal lobe epilepsy: Time is brain?

L Caciagli, A Bernasconi, S Wiebe, MJ Koepp… - Neurology, 2017 - AAN Enterprises
Objective: It remains unclear whether drug-resistant temporal lobe epilepsy (TLE) is
associated with cumulative brain damage, with no expert consensus and no quantitative …

The relevance of neuropsychiatric symptoms and cognitive problems in new-onset epilepsy—current knowledge and understanding

B Pohlmann-Eden, A Aldenkamp, GA Baker, C Brandt… - Epilepsy & behavior, 2015 - Elsevier
Neurobehavioral and cognition problems are highly prevalent in epilepsy, but most research
studies to date have not adequately addressed the precise nature of the relationship …

Epileptic prodromal Alzheimer's disease, a retrospective study of 13 new cases: expanding the spectrum of Alzheimer's disease to an epileptic variant?

B Cretin, F Sellal, N Philippi… - Journal of …, 2016 - content.iospress.com
Background: Aside from rare case reports, only one study, with 12 patients, has addressed
the phenotypic presentation of epilepsy in clinically defined amnestic mild cognitive …

Altered FMRI connectivity dynamics in temporal lobe epilepsy might explain seizure semiology

H Laufs, R Rodionov, R Thornton, JS Duncan… - Frontiers in …, 2014 - frontiersin.org
Temporal lobe epilepsy (TLE) can be conceptualized as a network disease. The network
can be characterized by inter-regional functional connectivity, ie, blood oxygen level …

Distinct limbic connectivity in left and right benign mesial temporal lobe epilepsy: Evidence from a resting state functional MRI study

C Pizzanelli, I Pesaresi, C Milano, P Cecchi… - Frontiers in …, 2022 - frontiersin.org
Background Functional connectivity (FC) studies showed that pharmaco-resistant mesial
temporal lobe epilepsy (MTLE) affects not only the limbic system, but also several extra …

Epilepsy, comorbidities and treatments

A Guekht - Current pharmaceutical design, 2017 - ingentaconnect.com
Background: An increasing amount of evidence suggests an association between epilepsy
and multiple somatic and psychiatric conditions, which is more significant than in the general …

Epileptic encephalopathies: optimizing seizure control and developmental outcome

L Jehi, E Wyllie, O Devinsky - Epilepsia, 2015 - Wiley Online Library
Cognitive and developmental outcomes in patients with epileptic encephalopathy are
hypothesized to result from an interplay between the underlying epileptic pathologic …

The effect of recurrent seizures on cognitive, behavioral, and quality-of-life outcomes after 12 months of monotherapy in adults with newly diagnosed or previously …

SA Lee, MJ Kim, HW Lee, K Heo, DJ Shin, HK Song… - Epilepsy & Behavior, 2015 - Elsevier
Purpose The purpose of this study was to determine whether seizure recurrence has a
negative impact on cognition, psychological function, and health-related quality of life …

The impact of right temporal lobe epilepsy on nonverbal memory: Meta-regression of stimulus-and task-related moderators

AC Bentvelzen, RPC Kessels, NA Badcock… - Neuropsychology …, 2022 - Springer
Nonverbal memory tests have great potential value for detecting the impact of lateralized
pathology and predicting the risk of memory loss following right temporal lobe resection …

Statistical learning in epilepsy: Behavioral and anatomical mechanisms in the human brain

A Aljishi, BE Sherman, DM Huberdeau, S Obaid… - …, 2024 - Wiley Online Library
Objective Statistical learning, the fundamental cognitive ability of humans to extract
regularities across experiences over time, engages the medial temporal lobe (MTL) in the …