Cancer cells display an altered metabolic phenotype, characterised by increased glycolysis
and lactate production, even in the presence of sufficient oxygen-a phenomenon known as …

Background Pyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by
pyruvate decarboxylation, which drives energy metabolism during cell growth, including …

Glioblastoma (GBM) is the most frequent and lethal primary malignant brain tumor. Despite
decades of research, therapeutic advances that significantly prolong life are non-existent. In …

Abstract Hsa‐microRNA‐215 (hsa‐miR‐215) plays multiple roles in carcinogenesis through
regulating its target genes. Genetic variants in hsa‐miR‐215 target sites thus may affect hsa …

Hepatic fibrosis can develop into cirrhosis or even cancer without active therapy at an early
stage. Long non-coding RNAs (lncRNAs) have been shown to be involved in the regulation …

To use bioinformatics and network analysis to reveal the mechanism of “Rhizoma Pinelliae-
Rhizoma Coptidis” herb pair in the treatment of lung adenocarcinoma. The target and …

ABSTRACT Methyltransferase like 3 (METTL3) has been reported to be dysregulated in
glioma. However, its role in aerobic glycolysis of glioma remains unknown. This study was …

The identification of expression quantitative trait loci (eQTL) is an important component in
efforts to understand how genetic variants influence disease risk. MicroRNAs (miRNAs) are …

The abnormal growth of cells in the prostate gland is what causes prostate cancer (PrCa).
Short tandem repeats (STRs) consist of 1–6 bp motifs repeated in tandem. We analysed …

Prostate cancer is the second most diagnosed and cause of cancer-related death in
Australian men. Resistance to treatment and non-specificity of the drugs is a major …