Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds
developed to probe the endogenous cannabinoid system or as potential therapeutics …

Abstract Context: Synthetic cannabinoids (SCs) such as “Spice”,“K2”, etc. are widely
available via the internet despite increasing legal restrictions. Currently, the prevalence of …

Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Indole and indazole synthetic cannabinoids (SCs) featuring l-valinate or l-tert-leucinate
pendant group have recently emerged as prevalent recreational drugs, and their use has …

Synthetic cannabinoid drugs have become an established part of the recreational drug
landscape in the United States and internationally. These drugs are manufactured in …

Cannabis use is associated with an increased risk of psychosis in vulnerable individuals.
Cannabis containing high levels of the partial cannabinoid receptor subtype 1 (CB1) agonist …

A number of N-alkyl indole or indazole-3-carbonyl analogs, with modified chemical
structures, are distributed throughout the world as synthetic cannabinoids. Like synthetic …

In the early 2000s in Europe and shortly thereafter in the USA, it was reported that
'legal'forms of marijuana were being sold under the name K2 and/or Spice. Active …

Abstract Introduction Synthetic cannabinoids (SCs) are psychoactive substances that are
gaining popularity for their availability and lack of detection by standardized drug tests …