[HTML][HTML] Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson, L Li - Analytical chemistry, 2018 - ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

Spatial metabolomics and imaging mass spectrometry in the age of artificial intelligence

T Alexandrov - Annual review of biomedical data science, 2020 - annualreviews.org
Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging

M Shariatgorji, A Nilsson, E Fridjonsdottir… - Nature …, 2019 - nature.com
We present a mass spectrometry imaging (MSI) approach for the comprehensive mapping of
neurotransmitter networks in specific brain regions. Our fluoromethylpyridinium-based …

MSiReader v1. 0: evolving open-source mass spectrometry imaging software for targeted and untargeted analyses

MT Bokhart, M Nazari, KP Garrard… - Journal of The …, 2017 - ACS Publications
A major update to the mass spectrometry imaging (MSI) software MSiReader is presented,
offering a multitude of newly added features critical to MSI analyses. MSiReader is a free …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Mass spectrometry imaging for clinical research–latest developments, applications, and current limitations

PM Vaysse, RMA Heeren, T Porta, B Balluff - Analyst, 2017 - pubs.rsc.org
Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

[HTML][HTML] Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer

C Bartolacci, C Andreani, G Vale, S Berto… - Nature …, 2022 - nature.com
Mutant KRAS (KM), the most common oncogene in lung cancer (LC), regulates fatty acid
(FA) metabolism. However, the role of FA in LC tumorigenesis is still not sufficiently …

Applications and continued evolution of glycan imaging mass spectrometry

CT McDowell, X Lu, AS Mehta… - Mass spectrometry …, 2023 - Wiley Online Library
Glycosylation is an important posttranslational modifier of proteins and lipid conjugates
critical for the stability and function of these macromolecules. Particularly important are N …