Advances in bladder cancer biology and therapy
The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …
generation sequencing has identified the genes most mutated in bladder cancer. This …
Sequencing-based methods and resources to study antimicrobial resistance
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
Urinary microbiome: yin and yang of the urinary tract
V Perez-Carrasco, A Soriano-Lerma… - Frontiers in cellular …, 2021 - frontiersin.org
The application of next generation sequencing techniques has allowed the characterization
of the urinary tract microbiome and has led to the rejection of the pre-established concept of …
of the urinary tract microbiome and has led to the rejection of the pre-established concept of …
The microbiome of the urinary tract—a role beyond infection
SA Whiteside, H Razvi, S Dave, G Reid… - Nature Reviews …, 2015 - nature.com
Urologists rarely need to consider bacteria beyond their role in infectious disease. However,
emerging evidence shows that the microorganisms inhabiting many sites of the body …
emerging evidence shows that the microorganisms inhabiting many sites of the body …
Advances in understanding the human urinary microbiome and its potential role in urinary tract infection
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …
identified a resident microbial community in the human urinary tract (UT). Compared to many …
Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
The female urinary microbiome: a comparison of women with and without urgency urinary incontinence
MM Pearce, EE Hilt, AB Rosenfeld, MJ Zilliox… - MBio, 2014 - Am Soc Microbiol
Bacterial DNA and live bacteria have been detected in human urine in the absence of
clinical infection, challenging the prevailing dogma that urine is normally sterile. Urgency …
clinical infection, challenging the prevailing dogma that urine is normally sterile. Urgency …
Urine is not sterile: use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder
EE Hilt, K McKinley, MM Pearce… - Journal of clinical …, 2014 - Am Soc Microbiol
Our previous study showed that bacterial genomes can be identified using 16S rRNA
sequencing in urine specimens of both symptomatic and asymptomatic patients who are …
sequencing in urine specimens of both symptomatic and asymptomatic patients who are …
Culturing of female bladder bacteria reveals an interconnected urogenital microbiota
Metagenomic analyses have indicated that the female bladder harbors an indigenous
microbiota. However, there are few cultured reference strains with sequenced genomes …
microbiota. However, there are few cultured reference strains with sequenced genomes …
The clinical urine culture: enhanced techniques improve detection of clinically relevant microorganisms
TK Price, T Dune, EE Hilt… - Journal of clinical …, 2016 - Am Soc Microbiol
Enhanced quantitative urine culture (EQUC) detects live microorganisms in the vast majority
of urine specimens reported as “no growth” by the standard urine culture protocol. Here, we …
of urine specimens reported as “no growth” by the standard urine culture protocol. Here, we …