The deleterious effects of chronically elevated free fatty acid (FFA) levels on glucose
homeostasis are referred to as lipotoxicity, and the concurrent exposure to high glucose may …

Serum albumin, commonly recognized as a predominant major plasma protein, is
ubiquitously distributed among vertebrates, demonstrating versatility and widespread …

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world.
High levels of free fatty acids in the liver impair hepatic lysosomal acidification and reduce …

Coronaviruses rely on host membranes for entry, establishment of replication centers, and
egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways …

Chromosome-containing micronuclei are a hallmark of aggressive cancers. Micronuclei
frequently undergo irreversible collapse, exposing their enclosed chromatin to the cytosol …

Abstract Changes in mitochondrial size and shape have been implicated in several
physiologic processes, but their role in mitochondrial Ca 2+ uptake regulation and overall …

Fatty acid (FA)-stimulated insulin secretion (FASIS) is reviewed here in contrast to type 2
diabetes etiology, resulting from FA overload, oxidative stress, intermediate …

Protein myristoylation is a C14 fatty acid modification found in all living organisms.
Myristoylation tags either the N-terminal alpha groups of cysteine or glycine residues …

CRISPR knockout fitness screens in cancer cell lines reveal many genes whose loss of
function causes cell death or loss of fitness or, more rarely, the opposite phenotype of faster …

Combined fatty acid esterification and lipolysis, termed lipid cycling, is an ATP‐consuming
process that contributes to energy expenditure. Therefore, interventions that stimulate …