Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

M Ishikura, T Abe, T Choshi, S Hibino - Natural product reports, 2015 - pubs.rsc.org
Covering: 2012 to 2013. Previous review: Nat. Prod. Rep., 2013, 30, 694–752 This review
covers the literature on simple indole alkaloids and those with a nonrearranged …

Cycloamination strategies for renewable N-heterocycles

H Li, H Guo, Z Fang, TM Aida, RL Smith - Green Chemistry, 2020 - pubs.rsc.org
Biomass resources have infinite possibilities for introducing nitrogen, sulfur, or phosphorus
heteroatoms into their structures by virtue of controllable carbon–heteroatom bond …

Natural product synthesis by C− H activation

SK Sinha, G Zanoni, D Maiti - Asian Journal of Organic …, 2018 - Wiley Online Library
The widespread use of transition‐metal‐mediated C− H bond activation has altered the field
of organic synthesis. Notwithstanding the immense effect this strategy has had on classical …

Dimethyl sulfoxide involved one-pot synthesis of quinoxaline derivatives

C Xie, Z Zhang, D Li, J Gong, X Han… - The Journal of organic …, 2017 - ACS Publications
An efficient, green, and novel method for the synthesis of N-heterocycle-fused quinoxalines
is reported herein. Dimethyl sulfoxide was used as both a reactant and a solvent in this …

Advancements in the synthesis of fused tetracyclic quinoline derivatives

RA Mekheimer, MA Al-Sheikh, HY Medrasi… - RSC advances, 2020 - pubs.rsc.org
Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …

Recent developments on synthesis and biological activities of γ-carboline

J Dai, W Dan, Y Zhang, J Wang - European journal of medicinal chemistry, 2018 - Elsevier
Abstract γ-Carboline alkaloids are a family of natural and synthetic agents that have diverse
bioactivities including antiviral, antibacterial, antifungal, antiparasitic, antitumor, anti …

A concise synthesis of indoloquinoline skeletons applying two consecutive Pd-catalyzed reactions

B Bogányi, J Kámán - Tetrahedron, 2013 - Elsevier
Abstract The indoloquinoline alkaloids cryptolepine (1), neocryptolepine (2), isocryptolepine
(3), and isoneocryptolepine (4) are important tools in traditional medicine. Now, their …

Radical Beckmann rearrangement and its application in the formal total synthesis of antimalarial natural product isocryptolepine via C–H activation

PS Mahajan, VT Humne, SD Tanpure… - Organic letters, 2016 - ACS Publications
The Beckmann rearrangement of ketoximes, mediated by ammonium persulfate-dimethyl
sulfoxide as a reagent, has been achieved under neutral conditions. Based on the radical …

Palladium-Catalyzed C-2 and C-3 Dual C–H Functionalization of Indoles: Synthesis of Fluorinated Isocryptolepine Analogues

C Chen, Y Wang, X Shi, W Sun, J Zhao, YP Zhu… - Organic …, 2020 - ACS Publications
Here we report a protocol to synthesize diversiform fluorinated isocryptolepine analogues
with potential biological activities in one step via directed C-2 and C-3 dual C–H …

Synthesis of isocryptolepine analogues and their structure–activity relationship studies as antiplasmodial and antiproliferative agents

P Aroonkit, C Thongsornkleeb, J Tummatorn… - European Journal of …, 2015 - Elsevier
Novel isocryptolepine analogues have been conveniently synthesized and evaluated for
antimalarial and antiproliferative activities. We have found 3-fluoro-8-bromo-isocryptolepine …