Human papillomaviruses: diversity, infection and host interactions

AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …

[HTML][HTML] Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation

AJ Kombe Kombe, B Li, A Zahid, HM Mengist… - Frontiers in public …, 2021 - frontiersin.org
Diagnosed in more than 90% of cervical cancers, the fourth deadliest cancer in women,
human papillomavirus (HPV) is currently the most common pathogen responsible for female …

[HTML][HTML] Human papillomavirus vaccine against cervical cancer: Opportunity and challenge

R Wang, W Pan, L Jin, W Huang, Y Li, D Wu, C Gao… - Cancer letters, 2020 - Elsevier
Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …

Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

[HTML][HTML] Opportunities and challenges for human papillomavirus vaccination in cancer

R Roden, PL Stern - Nature Reviews Cancer, 2018 - nature.com
The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

The biology and life-cycle of human papillomaviruses

J Doorbar, W Quint, L Banks, IG Bravo, M Stoler… - Vaccine, 2012 - Elsevier
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …

[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases

A Chabeda, RJR Yanez, R Lamprecht, AE Meyers… - Papillomavirus …, 2018 - Elsevier
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV …

Human papillomaviruses as infectious agents in gynecological cancers. oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

[HTML][HTML] The papillomavirus major capsid protein L1

CB Buck, PM Day, BL Trus - Virology, 2013 - Elsevier
The elegant icosahedral surface of the papillomavirus virion is formed by a single protein
called L1. Recombinant L1 proteins can spontaneously self-assemble into a highly …

[HTML][HTML] L2, the minor capsid protein of papillomavirus

JW Wang, RBS Roden - Virology, 2013 - Elsevier
The capsid protein L2 plays major roles in both papillomavirus assembly and the infectious
process. While L1 forms the majority of the capsid and can self-assemble into empty virus …