New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer's disease
F Zhang, R Zhong, C Cheng, S Li, W Le - Acta Pharmacologica Sinica, 2021 - nature.com
As the population ages, Alzheimer's disease (AD), the most common neurodegenerative
disease in elderly people, will impose social and economic burdens to the world. Currently …
disease in elderly people, will impose social and economic burdens to the world. Currently …
Association between statin use and cognitive function: a systematic review of randomized clinical trials and observational studies
A Adhikari, S Tripathy, S Chuzi, J Peterson… - Journal of Clinical …, 2021 - Elsevier
Abstract The US Food and Drug Administration issued a black box warning in 2012
regarding the association of statin use with cognitive impairment. This may deter patients …
regarding the association of statin use with cognitive impairment. This may deter patients …
What is the impact of ongoing statin use on cognitive decline and dementia progression in older adults with mild-moderate Alzheimer disease?
Background In addition to the clear cardiovascular benefit, there has been renewed interest
in the potential of statins in the prevention of cognitive impairment and dementia in older …
in the potential of statins in the prevention of cognitive impairment and dementia in older …
Detection of dementia progression from functional activities data using machine learning techniques
F Thabtah, S Ong, D Peebles - Intelligent Decision …, 2022 - content.iospress.com
Early screening for Alzheimer's disease (AD) is crucial for disease management,
intervention, and healthcare resource accessibility. Medical assessments of AD diagnosis …
intervention, and healthcare resource accessibility. Medical assessments of AD diagnosis …
The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
Statins are widely used for cardiovascular disease prevention but their effects on cognition
remain unclear. Statins reduce cholesterol concentration and have been suggested to …
remain unclear. Statins reduce cholesterol concentration and have been suggested to …
Statins and cognitive decline in patients with Alzheimer's and mixed dementia: a longitudinal registry-based cohort study
Background Disturbances in brain cholesterol homeostasis may be involved in the
pathogenesis of Alzheimer's disease (AD). Lipid-lowering medications could interfere with …
pathogenesis of Alzheimer's disease (AD). Lipid-lowering medications could interfere with …
[HTML][HTML] 降脂药物对认知功能影响的综述与前瞻
韩立君, 苏畅, 高聆 - Advances in Clinical Medicine, 2024 - hanspub.org
本综述探讨了降脂药物(包括他汀类, PCSK9 抑制剂, 依折麦布和贝特类)
对认知功能的潜在影响. 尽管有些研究和病例报告提示这些药物可能对认知有不良影响 …
对认知功能的潜在影响. 尽管有些研究和病例报告提示这些药物可能对认知有不良影响 …
Preventing lethal prostate cancer with diet, supplements, and rx: Heart healthy continues to be prostate healthy and “first do no harm” part II
MA Moyad - Current urology reports, 2020 - Springer
Abstract Purpose of Review To discuss the overall and latest observations of the effect of
diet, lifestyle, supplements, and some prescription heart healthy medications for prostate …
diet, lifestyle, supplements, and some prescription heart healthy medications for prostate …
Review of the protective effects of statins on cognition
B Chadha, WH Frishman - Cardiology in Review, 2021 - journals.lww.com
Elevated cholesterol is a major risk factor in the development of cardiovascular disease.
Statins have proven to be effective in lowering low-density lipoprotein cholesterol as well as …
Statins have proven to be effective in lowering low-density lipoprotein cholesterol as well as …
Statins and Alzheimer—current stand and further development directions
A Wełniak, P Koszykowska… - Medical Research …, 2020 - journals.viamedica.pl
In an aging society, more emphasis should be placed on prevention rather than treating
diseases. Alzheimer's disease is a common sickness affecting older people. It is predicted …
diseases. Alzheimer's disease is a common sickness affecting older people. It is predicted …