D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications

J Favresse, G Lippi, PM Roy, B Chatelain… - Critical reviews in …, 2018 - Taylor & Francis
D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …

Widely used types and clinical applications of D-dimer assay

RS Riley, AR Gilbert, JB Dalton, S Pai… - Laboratory …, 2016 - academic.oup.com
ABSTRACT D-dimers are formed by the breakdown of fibrinogen and fibrin during
fibrinolysis. D-dimer analysis is critical for the diagnosis of deep vein thrombosis, pulmonary …

[HTML][HTML] Markers of coagulation, fibrinolysis and inflammation in relation to post‐thrombotic syndrome

AC Bouman, JJM Smits, H Ten Cate… - Journal of Thrombosis …, 2012 - Elsevier
Background: Post‐thrombotic syndrome (PTS) occurs in 20–50% of patients after a deep
venous thrombosis (DVT). It is difficult to accurately predict which patients will develop PTS …

Prevalence of pulmonary embolism in patients with syncope

P Badertscher, J du Fay de Lavallaz… - Journal of the American …, 2019 - jacc.org
Background: The prevalence of pulmonary embolism (PE) in patients presenting with
syncope to the emergency department (ED) is largely unknown. This information, however …

D-dimer testing: A narrative review

L Wauthier, J Favresse, M Hardy, J Douxfils… - Advances in clinical …, 2023 - Elsevier
D-dimer containing species are soluble fibrin degradation products derived from plasmin-
mediated degradation of cross-linked fibrin, ie,'D-dimer'. D-dimer can hence be considered a …

D-dimer plasma level: a reliable marker for venous thromboembolism after elective craniotomy

J Prell, J Rachinger, R Smaczny, BM Taute… - Journal of …, 2013 - thejns.org
Object The incidence of deep venous thrombosis (DVT) after craniotomy is reported to be as
high as 50%. In outpatients, D-dimer levels of more than 0.5 mg/L indicate venous …

[HTML][HTML] Association of sleep problems with neuroendocrine hormones and coagulation factors in patients with acute myocardial infarction

R von Känel, M Princip, JP Schmid, J Barth… - BMC cardiovascular …, 2018 - Springer
Background Obstructive sleep apnea (OSA) and insomnia are frequent sleep problems that
are associated with poor prognosis in patients with coronary heart disease. The …

Longitudinal association between cognitive depressive symptoms and D‐dimer levels in patients following acute myocardial infarction

R von Känel, AP Pazhenkottil… - Clinical …, 2021 - Wiley Online Library
Background A prothrombotic tendency could partially explain the poor prognosis of patients
with coronary heart disease and depression. We hypothesized that cognitive depressive …

[HTML][HTML] D-dimer Testing in Pulmonary Embolism with a Focus on Potential Pitfalls: A Narrative Review

L Wauthier, J Favresse, M Hardy, J Douxfils, G Le Gal… - Diagnostics, 2022 - mdpi.com
D-dimer is a multifaceted biomarker of concomitant activation of coagulation and fibrinolysis,
which is routinely used for ruling out pulmonary embolism (PE) and/or deep vein thrombosis …

Prognostic value of D-dimer in elderly patients with Pulmonary Embolism

H Polo Friz, C Buzzini, A Orenti, V Punzi… - Journal of thrombosis …, 2016 - Springer
In a general population with acute Pulmonary Embolism (PE) elevated D-dimer
concentrations associate with increased mortality. The aim of the study was to assess the …