The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
[HTML][HTML] Dendrimers in the context of nanomedicine
AP Dias, S da Silva Santos, JV da Silva… - International journal of …, 2020 - Elsevier
Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …
radially from the core and terminal groups on the surface, resembling tree architecture …
Advances in the sensing and treatment of wound biofilms
Wound biofilms represent a particularly challenging problem in modern medicine. They are
increasingly antibiotic resistant and can prevent the healing of chronic wounds. However …
increasingly antibiotic resistant and can prevent the healing of chronic wounds. However …
[HTML][HTML] An update on antimicrobial peptides (AMPs) and their delivery strategies for wound infections
Bacterial infections occur when wound healing fails to reach the final stage of healing, which
is usually hindered by the presence of different pathogens. Different topical antimicrobial …
is usually hindered by the presence of different pathogens. Different topical antimicrobial …
Fluorescence imaging of bacterial killing by antimicrobial peptide dendrimer G3KL
We recently discovered that peptide dendrimers such as G3KL ((KL) 8 (K KL) 4 (K KL) 2 K
KL, K= branching l-lysine) exert strong activity against Gram-negative bacteria including …
KL, K= branching l-lysine) exert strong activity against Gram-negative bacteria including …
[HTML][HTML] Antimicrobial peptides for tackling cystic fibrosis related bacterial infections: A review
Antibiotic resistance is a serious health and social problem that will have a substantial
impact in the coming years on the world health and economy. Thus, the increasing demand …
impact in the coming years on the world health and economy. Thus, the increasing demand …
Approaches for mitigating microbial biofilm-related drug resistance: a focus on micro-and nanotechnologies
H Rao, S Choo, SR Rajeswari Mahalingam, DS Adisuri… - Molecules, 2021 - mdpi.com
Biofilms play an essential role in chronic and healthcare-associated infections and are more
resistant to antimicrobials compared to their planktonic counterparts due to their (1) …
resistant to antimicrobials compared to their planktonic counterparts due to their (1) …
[HTML][HTML] An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening
Membrane-disruptive amphiphilic antimicrobial peptides behave as intrinsically disordered
proteins by being unordered in water and becoming α-helical in contact with biological …
proteins by being unordered in water and becoming α-helical in contact with biological …
Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications
Pathogenic bacteria cause the deaths of millions of people every year. With the
development of antibiotics, hundreds and thousands of people's lives have been saved …
development of antibiotics, hundreds and thousands of people's lives have been saved …
Synergistic effect of propidium iodide and small molecule antibiotics with the antimicrobial peptide dendrimer G3KL against gram-negative bacteria
There is an urgent need to develop new antibiotics against multidrug-resistant bacteria.
Many antimicrobial peptides (AMPs) are active against such bacteria and often act by …
Many antimicrobial peptides (AMPs) are active against such bacteria and often act by …