Microbiome-based therapeutics
MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Analysis of the clinical pipeline of treatments for drug-resistant bacterial infections: despite progress, more action is needed
MS Butler, V Gigante, H Sati, S Paulin… - Antimicrobial agents …, 2022 - Am Soc Microbiol
There is an urgent global need for new strategies and drugs to control and treat multidrug-
resistant bacterial infections. In 2017, the World Health Organization (WHO) released a list of …
resistant bacterial infections. In 2017, the World Health Organization (WHO) released a list of …
[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies
D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …
use and residues of antibiotics in humans, animals, and the environment can exert selective …
Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome
A Crits-Christoph, HA Hallowell, K Koutouvalis… - Gut …, 2022 - Taylor & Francis
ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …
Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection
Fecal microbiota transplantation (FMT) is highly effective in preventing recurrent
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …
Clostridioides difficile infection (rCDI). However, the mechanisms underpinning its clinical …
Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials
C Lee, T Louie, L Bancke… - Therapeutic …, 2023 - journals.sagepub.com
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …
The role of the gut microbiome in colonization resistance and recurrent Clostridioides difficile infection
AM Seekatz, N Safdar… - Therapeutic Advances in …, 2022 - journals.sagepub.com
The species composition of the human gut microbiota is related to overall health, and a
healthy gut microbiome is crucial in maintaining colonization resistance against pathogens …
healthy gut microbiome is crucial in maintaining colonization resistance against pathogens …
Gut microbiota changes associated with Clostridioides difficile infection and its various treatment strategies
Human gut microbiota are critical to both the development of and recovery from
Clostridioides difficile infection (CDI). Antibiotics are the mainstay of CDI treatment, yet …
Clostridioides difficile infection (CDI). Antibiotics are the mainstay of CDI treatment, yet …
[HTML][HTML] Antibiotic resistance monitoring in wastewater in the Nordic countries: A systematic review
Abstract The Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden) have
effectively kept lower antibiotic-resistant bacterial (ARB) pathogen rates than many other …
effectively kept lower antibiotic-resistant bacterial (ARB) pathogen rates than many other …
Impact of international travel and diarrhea on gut microbiome and resistome dynamics
M Boolchandani, KS Blake, DH Tilley… - Nature …, 2022 - nature.com
International travel contributes to the global spread of antimicrobial resistance. Travelers'
diarrhea exacerbates the risk of acquiring multidrug-resistant organisms and can lead to …
diarrhea exacerbates the risk of acquiring multidrug-resistant organisms and can lead to …