[HTML][HTML] Oxidative stress, inflammation and colorectal cancer: an overview

A Bardelčíková, J Šoltys, J Mojžiš - Antioxidants, 2023 - mdpi.com
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

[HTML][HTML] Mechanisms of sex differences in Alzheimer's disease

C Lopez-Lee, ERS Torres, G Carling, L Gan - Neuron, 2024 - cell.com
Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

[HTML][HTML] Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer

R Yang, Y Han, X Guan, Y Hong, J Meng… - Cell Communication and …, 2023 - Springer
Telomerase reverse transcriptase (TERT/hTERT) serves as the pivotal catalytic subunit of
telomerase, a crucial enzyme responsible for telomere maintenance and human genome …

Telomerase activity and telomere length in women with breast cancer or without malignancy: A systematic review and meta-analysis

VA Benites-Zapata, JR Ulloque-Badaracco… - Maturitas, 2023 - Elsevier
Aim We performed a systematic review and meta-analysis to assess whether telomerase
activity and telomere length are associated with breast cancer. Methods PubMed, Web of …

Prostate Cancer and the Mevalonate Pathway

P Guerrero-Ochoa, S Rodríguez-Zapater… - International Journal of …, 2024 - mdpi.com
Antineoplastic therapies for prostate cancer (PCa) have traditionally centered around the
androgen receptor (AR) pathway, which has demonstrated a significant role in oncogenesis …

Interleukin-15 in kidney disease and therapeutics

G Hall - Current Opinion in Nephrology and Hypertension, 2024 - journals.lww.com
The cytoprotective properties of IL-15 suggest that it may have potential as a
nonimmunosuppresive therapeutic for kidney disease. A novel class of IL-15 …

[HTML][HTML] The dual activity of CaONPs as a cancer treatment substance and at the same time resistance to harmful microbes

A Awaad, ZA Olama, GM El-Subruiti, SM Ali - Scientific Reports, 2023 - nature.com
Nanotechnology holds significant promise for the development of novel and necessary
products that enhance human health. Pharmacology and nanotechnology have contributed …

Endometrial telomerase activity in women with either endometrial cancer or hyperplasia: A systematic review and meta-analysis

FR Pérez-López, JR Ulloque-Badaracco… - Maturitas, 2023 - Elsevier
Aim We performed a systematic review and meta-analysis to assess whether endometrial
telomerase activity is associated with endometrial cancer or hyperplasia. Methods PubMed …

[HTML][HTML] Novel biomarkers used for early diagnosis and tyrosine kinase inhibitors as targeted therapies in colorectal cancer

H Jiang, S Zhou, G Li - Frontiers in pharmacology, 2023 - frontiersin.org
Colorectal cancer (CRC) is the third most common and second most lethal type of cancer
worldwide, presenting major health risks as well as economic costs to both people and …

Upregulation of shelterin and CST genes and longer telomeres are associated with unfavorable prognostic characteristics in prostate cancer

GA Dos Santos, NI Viana, R Pimenta, JA de Camargo… - Cancer Genetics, 2024 - Elsevier
Introduction Search for new clinical biomarkers targets in prostate cancer (PC) is urgent.
Telomeres might be one of these targets. Telomeres are the extremities of linear …